Small cell lung cancer and anti-Hu syndrome

被引：5

作者：

Prim, N. ^{[1
]}

Mennecier, B. ^{[1
]}

Behr, C. ^{[2
]}

Fraisse, P. ^{[1
]}

Echaniz-Laguna, A. ^{[2
]}

Tranchant, C. ^{[2
]}

Quoix, E. ^{[1
]}

机构：

[1] Hop Univ Strasbourg 1, Serv Pneumol, F-67091 Strasbourg, France

[2] Hop Univ, Serv Neurol, Strasbourg, France

来源：

REVUE DES MALADIES RESPIRATOIRES | 2010年 / 27卷 / 03期

关键词：

Small-cell lung cancer; Paraneoplastic syndrome; Anti-Hu antibodies; Dysautonomia; Gastroparesia; PARANEOPLASTIC NEUROLOGICAL SYNDROMES; ANTIBODIES; ENCEPHALOMYELITIS;

D O I：

10.1016/j.rmr.2010.02.006

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Introduction. The anti-Hu associated syndrome is a rare paraneoplastic neurological syndrome, which is principally associated with small-cell lung cancer. Observation. We report the case of a patient with the following clinical features: dysautonomia with severe gastroparesis, sensory neuropathy and a rhombencephalitis. Tumour regression was obtained with chemotherapy but the patient ultimately died from the neurological complications. Conclusion. Neurological syndromes associated in small cell lung cancer with anti-Hu antibodies are very diverse. Cancer evolution is generally speaking more benign than usual with the prognosis linked to the severity of the neurological involvement. (C) 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：261 / 265

页数：5

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