Isoprenoid intermediates in the cholesterol pathway determine the fate of pathogenic T cells during CNS autoimmunity

被引：0
|
作者：
Youssef, S.
Dunn, S. E.
Zamvil, S. S.
Steinman, L.
机构：
[1] Stanford Univ, Stanford, CA 94305 USA
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
来源：
MULTIPLE SCLEROSIS | 2007年 / 13卷 / 02期
关键词：
atorvastatin; EAE; farnesyl-pyrophosphate; geranylgeranyl-pyrophosphate; HMG-CoA reductase; Th1/Th2;
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：298 / 299
页数：2
相关论文
共 50 条
  • [1] Hybrid αβ-γδ T cells, novel T cell populations with a critical pathogenic role in CNS autoimmunity
    Edwards, S. C.
    Sutton, C. E.
    McLaren, J. E.
    Ladell, K.
    Ribot, J. C.
    Baik, S.
    Moran, B.
    Anderson, G.
    Silva-Santos, B.
    Price, D. A.
    Mills, K. H. G.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2016, 46 : 256 - 256
  • [2] Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin
    Dunn, SE
    Youssef, S
    Goldstein, MJ
    Prod'homme, T
    Weber, MS
    Zamvil, SS
    Steinman, L
    JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (02): : 401 - 412
  • [3] γδ T cells and NK cells - distinct pathogenic roles as innate-like immune cells in CNS autoimmunity
    Edwards, Sarah C.
    McGinley, Aoife M.
    McGuinness, Niamh C.
    Mills, Kingston H. G.
    FRONTIERS IN IMMUNOLOGY, 2015, 6
  • [4] γβ T cells, a novel T cell subset with a pathogenic role in IL-17-mediated CNS autoimmunity
    Edwards, Sarah C.
    Sutton, Caroline E.
    Mills, Kingston H. G.
    CYTOKINE, 2014, 70 (01) : 37 - 38
  • [5] Editorial: Pathogenic roles of T cells in autoimmunity
    Xia, Jinfang
    Tang, Jifeng
    Fu, Qiong
    Lin, Jinpiao
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [6] Heterogeneity of Myeloid Cells During CNS Autoimmunity
    Ardestani, N. Manouchehri
    Salinas, V.
    Hussain, R.
    Stuve, O.
    MULTIPLE SCLEROSIS JOURNAL, 2022, 28 (1_SUPPL) : 10 - 11
  • [7] Retinoic acid suppresses IL-17 production and pathogenic activity of γδ T cells in CNS autoimmunity
    Raverdeau, Mathilde
    Breen, Conor J.
    Misiak, Alicja
    Mills, Kingston H. G.
    IMMUNOLOGY AND CELL BIOLOGY, 2016, 94 (08): : 763 - 773
  • [8] YB T cells; a novel T cell subset with a pathogenic role in il-17-mediated cns autoimmunity
    Edwards, S. C.
    Sutton, C. E.
    Mills, K. H. G.
    IRISH JOURNAL OF MEDICAL SCIENCE, 2015, 184 : 12 - 12
  • [9] Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway During Neuronal Differentiation In Vitro
    Cartocci, Veronica
    Segatto, Marco
    Di Tunno, Ilenia
    Leone, Stefano
    Pfrieger, Frank W.
    Pallottini, Valentina
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2016, 117 (09) : 2036 - 2044
  • [10] γβ T-cells, a novel T-cell subset with a pathogenic role in IL-17-mediated CNS autoimmunity
    Edwards, S. C.
    Sutton, C. E.
    Mills, K. H. G.
    IMMUNOLOGY, 2014, 143 : 51 - 51
12345