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Efficient -catalyzed synthesis of novel and diverse 2,3-dihydroquinazolin-4(1)-ones
被引:0
|作者:
Zhu, Xiaoyan
[1
]
Kang, So Rang
[1
]
Xia, Likai
[1
]
Lee, Jihye
[1
]
Basavegowda, Nagaraj
[1
]
Lee, Yong Rok
[1
]
机构:
[1] Yeungnam Univ, Sch Chem Engn, Gyongsan 712749, South Korea
关键词:
2;
3-Dihydroquinazolin-4(1H)-ones;
Isatoic anhydride;
Ketones;
Amines;
MCRs;
Copper(II) trifluoromethanesulfonate;
ONE-POT;
ENANTIOSELECTIVE SYNTHESIS;
COMBINATORIAL SYNTHESIS;
ASYMMETRIC-SYNTHESIS;
3-COMPONENT REACTION;
IONIC LIQUIDS;
DERIVATIVES;
WATER;
QUINAZOLIN-4(3H)-ONES;
ALKALOIDS;
D O I:
10.1007/s11030-014-9557-z
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
An efficient one-pot synthesis of various 2,3-dihydroquinazolin--one derivatives was accomplished using -catalyzed multi-component reactions between isatoic anhydride, ketones, and amines. The method has several significant advantages; mild reaction conditions, easy handling, and efficiency of catalyst.
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页码:67 / 75
页数:9
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