A selective 5-HT4 receptor antagonist blocks the effect of tegaserod on rat inferior splanchnic afferents in vitro

被引:0
|
作者
Wang, YH
Wei, JY
Mayer, EA
机构
关键词
D O I
10.1016/S0016-5085(03)82880-9
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:A569 / A569
页数:1
相关论文
共 50 条
  • [41] QUATERNIZED RENZAPRIDE AS A POTENT AND SELECTIVE 5-HT4 RECEPTOR AGONIST
    BAXTER, GS
    BOYLAND, P
    GASTER, LM
    KING, FD
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (04) : 633 - 634
  • [42] Different expression of 5-HT4 receptor (5-HT4R) transcripts correlates with the functional responses of tegaserod on chloride/water secretion in the human ileum and colon in vitro
    Ito, Moriko
    Weber, Eckhard
    Hamel, Christian T.
    Bernhard, Mario
    Marcaletti, Stephan
    Mueller, Ursula
    Bassilana, Frederic
    Pfannkuche, Hans-Juergen
    GASTROENTEROLOGY, 2006, 130 (04) : A544 - A544
  • [43] Effect of ATI-7505, a selective 5-HT4 receptor agonist, on gastric emptying
    Choppin, A
    Palme, M
    Otterson, M
    Dennis, D
    Jacoby, H
    Druzgala, P
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2005, 100 (09): : S58 - S59
  • [44] INTRANIGRAL GR-113808, A SELECTIVE 5-HT4 RECEPTOR ANTAGONIST, ATTENUATES MORPHINE-STIMULATED DOPAMINE RELEASE IN THE RAT STRIATUM
    POZZI, L
    TRABACE, L
    INVERNIZZI, R
    SAMANIN, R
    BRAIN RESEARCH, 1995, 692 (1-2) : 265 - 268
  • [45] Td-5108, a selective, high intrinsic activity 5-HT4 receptor agonist -: In vitro profile at human recombinant 5-HT4 receptor splice variant and human isolated colon
    Smith, Jacqueline
    Beattie, David T.
    Cuthbert, Alan W.
    Ropenga, Anna
    Marquess, Daniel
    Shaw, Jeng-Peng
    Vickery, Ross
    Humphrey, Patrick P.
    GASTROENTEROLOGY, 2007, 132 (04) : A687 - A687
  • [46] Ability of 5-HT4 receptor ligands to modulate rat striatal dopamine release in vitro and in vivo
    Steward, LJ
    Ge, J
    Stowe, RL
    Brown, DC
    Bruton, RK
    Stokes, PRA
    Barnes, NM
    BRITISH JOURNAL OF PHARMACOLOGY, 1996, 117 (01) : 55 - 62
  • [47] Tegaserod -: A serotonin 5-HT4 receptor agonist for treatment of constipation-predominant irritable bowel syndrome
    Cole, P
    Rabasseda, X
    DRUGS OF TODAY, 2004, 40 (12) : 1013 - 1030
  • [48] Stimulation of intestinal gas dynamics by the 5-HT4 receptor agonist tegaserod in healthy humans with gas retention
    Coleski, R
    Owyang, C
    Hasler, WL
    GASTROENTEROLOGY, 2004, 126 (04) : A100 - A101
  • [49] RS-100235 - A HIGH-AFFINITY 5-HT4 RECEPTOR ANTAGONIST
    CLARK, RD
    JAHANGIR, A
    FLIPPIN, LA
    LANGSTON, JA
    LEUNG, E
    BONHAUS, DW
    WONG, EHF
    JOHNSON, LG
    EGLEN, RM
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (18) : 2119 - 2122
  • [50] Tegaserod, a 5-HT4 receptor partial agonist, relieves key symptoms of irritable bowel syndrome (IBS).
    Mueller-Lissner, S
    Fumagalli, I
    Bardhan, KD
    Pace, F
    Nault, B
    Pecher, EC
    Rueegg, PC
    Lefkowitz, MP
    GASTROENTEROLOGY, 2000, 118 (04) : A175 - A175