The FANCM family of DNA helicases/translocases

被引：86

作者：

Whitby, Matthew C. ^{[1
]}

机构：

[1] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England

来源：

DNA REPAIR | 2010年 / 9卷 / 03期

基金：

英国惠康基金;

关键词：

FANCM; Mph1; Fml1; Hef; Homologous recombination; Fanconi Anemia; ANEMIA CORE COMPLEX; HOMOLOGOUS RECOMBINATION; CELL-CYCLE; SACCHAROMYCES-CEREVISIAE; MONOUBIQUITINATED FANCD2; PROMOTES RECOMBINATION; REPLICATION FORKS; CROSSING-OVER; MPH1; GENE; PROTEIN;

D O I：

10.1016/j.dnarep.2009.12.012

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

FANCM and its relatives, Hef, Mph1 and Fml1, are DNA junction-specific helicases/translocases that target and process perturbed replication forks and intermediates of homologous recombination. They have variously been implicated in promoting the activation of the S-phase checkpoint, recruitment of the Fanconi Anemia Core Complex to sites of DNA damage, crossover avoidance during DNA double-strand break repair by homologous recombination, This review summarises our current understanding of the biochemical activities and biological functions and the replicative bypass of DNA lesions by template switching. of the FANCM family. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：224 / 236

页数：13

共 50 条

[21] RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability
Sharma, Sudha
Stumpo, Deborah J.
Balajee, Adayabalam S.
Bock, Cheryl B.
Lansdorp, Peter M.
Brosh, Robert M., Jr.
Blackshear, Perry J.
[J]. MOLECULAR AND CELLULAR BIOLOGY, 2007, 27 (05) : 1784 - 1794
[22] A skipping rope translocation mechanism in a widespread family of DNA repair helicases
Roske, Johann J.
Liu, Sunbin
Loll, Bernhard
Neu, Ursula
Wahl, Markus C.
[J]. NUCLEIC ACIDS RESEARCH, 2021, 49 (01) : 504 - 518
[23] Branched unwinding mechanism of the Pif1 family of DNA helicases
Singh, Saurabh P.
Soranno, Andrea
Sparks, Melanie A.
Galletto, Roberto
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (49) : 24533 - 24541
[24] Eukaryotic DNA helicases
Enomoto, T
[J]. SEIKAGAKU, 1996, 68 (11): : 1708 - 1713
[25] EUKARYOTIC DNA HELICASES
THOMMES, P
HUBSCHER, U
[J]. FEBS LETTERS, 1990, 268 (02) : 325 - 328
[26] History of DNA Helicases
Brosh, Robert M., Jr.
Matson, Steven W.
[J]. GENES, 2020, 11 (03)
[27] Division of Labor by the HELQ, BLM, and FANCM Helicases during Homologous Recombination Repair in Drosophila melanogaster
Thomas, Adam
Cox, Julie
Wolfe, Kelly B.
Mingalone, Carrie Hui
Yaspan, Haleigh R.
McVey, Mitch
[J]. GENES, 2022, 13 (03)
[28] The RecQ DNA Helicases in DNA Repair
Bernstein, Kara A.
Gangloff, Serge
Rothstein, Rodney
[J]. ANNUAL REVIEW OF GENETICS, VOL 44, 2010, 44 : 393 - 417
[29] A conserved G4 DNA binding domain in RecQ family helicases
Huber, Michael D.
Duquette, Michelle L.
Shiels, Jerome C.
Maizels, Nancy
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2006, 358 (04) : 1071 - 1080
[30] Getting it done at the ends: Pif1 family DNA helicases and telomeres
Geronimo, Carly L.
Zakian, Virginia A.
[J]. DNA REPAIR, 2016, 44 : 151 - 158

← 1 2 3 4 5 →