Waveguide-based absorption measurement system for visible wavelength applications

被引:4
|
作者
Neutens, P. [1 ]
Jansen, R. [1 ]
Woronoff, G. [1 ]
Rutowska, M. [1 ]
Hosseini, N. [1 ]
Buja, F. [1 ]
Humbert, A. [1 ]
Colle, F. [1 ]
Stakenborg, T. [1 ]
Van Roy, W. [1 ]
机构
[1] IMEC, Kapeldreef 75, B-3001 Leuven, Belgium
来源
BIOMEDICAL OPTICS EXPRESS | 2021年 / 12卷 / 04期
关键词
D O I
10.1364/BOE.418264
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present a miniaturized waveguide-based absorption measurement system operating at a wavelength of 635 nm, based on a silicon nitride integrated photonic platform, suitable for lab-on-chip applications. We experimentally demonstrate a high correlation between the bulk dye concentration and the measured absorption loss levels in the waveguides. We explain a photonic design process for choosing the ideal waveguide to minimize the coefficient of variation on the analyte concentration. The approach is designed for camera readout, allowing multiple readouts and easy integration for lab-on chip cartridge approach.
引用
收藏
页码:2041 / 2053
页数:13
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