Hyperammonemia Induced Skeletal Muscle Mitochondrial Dysfunction Is Mediated By a Novel DRP1 Modification Induced Fission

被引:0
|
作者
Davuluri, Gangarao [1 ]
Kumar, Avinash [2 ]
Gangadhariah, Mahesha [2 ]
Kant, Sashi [1 ]
Clinton, Ryan [3 ]
Singh, Kulwant Aulak [2 ]
Qi, Xin [4 ]
Hoppel, Charles [3 ]
Mears, Jason [3 ]
Dasarathy, Srinivasan [2 ,5 ]
机构
[1] Cleveland Clin Fdn, Inflamat & Immun, Cleveland, OH USA
[2] Cleveland Clin Fdn, Inflammat & Immun, Cleveland, OH USA
[3] Case Western Reserve Univ, Pharmacol, Cleveland, OH 44106 USA
[4] Case Western Reserve Univ, Physiol, Cleveland, OH 44106 USA
[5] Cleveland Clin, Inflammat & Immun, Cleveland, OH 44106 USA
基金
美国国家卫生研究院;
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
843
引用
收藏
页码:498A / 498A
页数:1
相关论文
共 50 条
  • [1] Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension
    Tian, Lian
    Neuber-Hess, Monica
    Mewburn, Jeffrey
    Dasgupta, Asish
    Dunham-Snary, Kimberly
    Wu, Danchen
    Chen, Kuang-Hueih
    Hong, Zhigang
    Sharp, Willard W.
    Kutty, Shelby
    Archer, Stephen L.
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2017, 95 (04): : 381 - 393
  • [2] Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension
    Lian Tian
    Monica Neuber-Hess
    Jeffrey Mewburn
    Asish Dasgupta
    Kimberly Dunham-Snary
    Danchen Wu
    Kuang-Hueih Chen
    Zhigang Hong
    Willard W. Sharp
    Shelby Kutty
    Stephen L. Archer
    Journal of Molecular Medicine, 2017, 95 : 381 - 393
  • [3] Recruitment of Drp1 in Mitochondrial Fission
    Egner, John M.
    Bakkum, Amber
    Gardner, Alex
    Hill, Blake
    FASEB JOURNAL, 2017, 31
  • [4] ALCOHOL CAUSES SKELETAL MUSCLE MITOCHONDRIAL FISSION AND DYSFUNTION BY DEPHOSPHORYLATION OF DRP1 AT SER 636
    Davuluri, G.
    McMullen, M.
    McCullough, R.
    NagaPrasad, S. V.
    Mohan, M.
    Nagy, L. E.
    Dasarathy, S.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2016, 40 : 132A - 132A
  • [5] The role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity
    Chen, Yan
    Yan, Lili
    Zhang, Yan
    Yang, Xianhui
    ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2019, 47 (01) : 1788 - 1796
  • [6] Sarcopenia in cirrhosis is caused by hyperammonemia induced skeletal muscle mitochondrial dysfunction
    Thapaliya, Samjhana
    Fealy, Ciaran E.
    Mulya, Anny
    Flask, Chris A.
    Kirwan, John P.
    Dasarathy, Srinivasan
    HEPATOLOGY, 2013, 58 : 459A - 459A
  • [7] Metformin Protects Against Diabetes-Induced Cognitive Dysfunction by Inhibiting Mitochondrial Fission Protein DRP1
    Hu, Yan
    Zhou, Yile
    Yang, Yajie
    Tang, Haihong
    Si, Yuan
    Chen, Zhouyi
    Shi, Yi
    Fang, Hao
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [8] ROLE OF DRP1/FIS1-MEDIATED MITOCHONDRIAL FRAGMENTATION IN SEPSIS-INDUCED MYOCARDIAL DYSFUNCTION
    Haileselassie, Bereketeab
    Joshi, Amit
    Mukherjee, Riddhita
    Napier, Brooke Napier
    Massis, Liliana
    Ostberg, Nicolai
    Monack, Denise
    Bernstein, Daniel
    Mochly-Rosen, Daria
    CRITICAL CARE MEDICINE, 2019, 47
  • [9] Mitochondrial fission requires DRP1 but not dynamins
    Fonseca, Tiago Branco
    Sanchez-Guerrero, Angela
    Milosevic, Ira
    Raimundo, Nuno
    NATURE, 2019, 570 (7761) : E34 - E42
  • [10] Mitochondrial fission requires DRP1 but not dynamins
    Tiago Branco Fonseca
    Ángela Sánchez-Guerrero
    Ira Milosevic
    Nuno Raimundo
    Nature, 2019, 570 : E34 - E42