Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas

被引：11
|
作者：
Furukawa, Toru [1 ]
机构：
[1] Tokyo Womens Med Univ, Int Res & Educ Inst Integrated Med Sci, Shinjuku Ku, Tokyo 1628666, Japan
来源：
JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY | 2007年 / 14卷 / 03期
关键词：
IPMN; PanIN; pancreatic cancer; SMAD4; DUSP6;
D O I：
10.1007/s00534-006-1167-4
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Intraductal papillary-mucinous neoplasms of the pancreas show characteristic clinicopathological and molecular pathobiological features which are distinct from those of conventional ductal adenocarcinomas. Alterations of KRAS, AKT/PKB, CDKN2A, TP53, SMAD4, STK11/LKB1, and DUSP6, and other molecular alterations, including global expression studies as well as their clinical implications, are discussed.
引用
收藏
页码：233 / 237
页数：5
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