Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy

被引：9

作者：

Yang, Andrew I. ^{[1
]}

Khawaja, Ayaz M. ^{[2
]}

Ballester-Fuentes, Leo ^{[3
]}

Pack, Svetlana D. ^{[3
]}

Abdullaev, Ziedulla ^{[3
]}

Patronas, Nicholas J. ^{[4
]}

Inati, Sara K. ^{[5
]}

Theodore, William H. ^{[6
]}

Quezado, Martha M. ^{[3
]}

Zaghloul, Kareem A. ^{[1
]}

机构：

[1] NINDS, Surg Neurol Branch, NIH, Bethesda, MD 20892 USA

[2] Univ Alabama Birmingham, Dept Neurol, Birmingham, AL 35294 USA

[3] NCI, Pathol Lab, NIH, Bethesda, MD 20892 USA

[4] NIH, Neuroradiol Sect, Warren Grant Magnuson Clin Ctr, Bethesda, MD 20892 USA

[5] NINDS, EEG Sect, NIH, Bethesda, MD 20892 USA

[6] NINDS, Clin Epilepsy Sect, NIH, Bethesda, MD 20892 USA

来源：

EPILEPTIC DISORDERS | 2014年 / 16卷 / 03期

基金：

美国国家卫生研究院;

关键词：

multi-focal tumor; tumor-associated epilepsy; Chiari malformation;

D O I：

10.1684/epd.2014.0680

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour-associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra- and supra-tentorial locations, in a 23-year-old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.

引用

页码：328 / 332

页数：5

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