Targeting the TNFR2 oncogene on tumor cells and tregs of the tumor microenvironment via dominant TNFR2 antagonism.

被引:0
|
作者
Faustman, Denise L.
Torrey, Heather
Butterworth, John
Mera, Toshi
Okubo, Yoshiaki
Wang, Limei
Baum, Danielle
Warden, Sara
Plager, Sarah
Huang, Daniel
Vanamee, Eva
Foster, Rosemary
机构
[1] Massachusetts Gen Hosp, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
关键词
D O I
10.1200/JCO.2017.35.7_suppl.106
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
106
引用
收藏
页数:1
相关论文
共 50 条
  • [21] The tumor suppressor SOCS3 limits STAT3 binding to the TNFR2 promoter and promotes proteasomal degradation of TNFR2
    Hamilton, Kathryn Elizabeth
    Simmons, James G.
    Rigby, Rachael J.
    Lund, P. Kay
    FASEB JOURNAL, 2009, 23
  • [22] Tumor Necrosis Factor-alpha, TNFR1, and TNFR2 Responses to Exercise in the Heat
    Arroyo, Eliott
    Followay, Brittany N.
    Vaughan, Jeremiah A.
    Laudato, Joseph A.
    Gibson, Brandon M.
    Glickman, Ellen L.
    Jajtner, Adam R.
    FASEB JOURNAL, 2018, 32 (01):
  • [23] The Immunosuppressive Effect of TNFR2 Expression in the Colorectal Cancer Microenvironment
    Salim, Nurul Hakimah Mohd
    Mussa, Ali
    Ahmed, Naveed
    Ahmad, Suhana
    Yean, Chan Yean
    Hassan, Rosline
    Uskokovic, Vuk
    Mohamud, Rohimah
    Jalil, Nur Asyilla Che
    BIOMEDICINES, 2023, 11 (01)
  • [24] Biomechanical strain regulates TNFR2 but not TNFR1 in TMJ cells
    Deschner, James
    Rath-Deschner, Birgit
    Wypasek, Ewa
    Anghelina, Mirela
    Sjostrom, Danen
    Agarwal, Sudha
    JOURNAL OF BIOMECHANICS, 2007, 40 (07) : 1541 - 1549
  • [25] TNFR2 signalling in inflammatory diseases
    Williams, Richard O.
    Clanchy, Felix IL.
    Huang, Yi-Shu
    Tseng, Wen-Yi
    Stone, Trevor W.
    BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2024, 38 (02):
  • [26] Novel TNFR2 Signaling in Osteoarthritis
    Fu, Wenyu
    Yi, Young-Su
    Mundra, Jyoti Joshi
    Hettinghouse, Aubryanna
    Liu, Chuanju
    JOURNAL OF BONE AND MINERAL RESEARCH, 2018, 33 : 220 - 220
  • [27] Generation and validation of a novel humanized TNFR2 mouse model for the evaluation of therapeutic TNFR2 antibody.
    Zhao, Xiaofeng
    Pang, Ran
    Liu, Xiaoqing
    Li, Wenjing
    He, Xianfei
    Ouyang, Xuesong
    Cao, Zhuoxiao
    Tang, Renhong
    Yang, Wenqing
    CANCER RESEARCH, 2021, 81 (13)
  • [28] TNFR2: The new Treg switch?
    Cohen, Jose E. L.
    Wood, Kathryn J.
    ONCOIMMUNOLOGY, 2018, 7 (01):
  • [29] Role of the tumor necrosis factor receptor 2 (TNFR2) in cerebral malaria in mice
    Piguet, PF
    Da Kan, C
    Vesin, C
    LABORATORY INVESTIGATION, 2002, 82 (09) : 1155 - 1166
  • [30] Tumor Necrosis Factor Receptor 2 (TNFR2): An Emerging Target in Cancer Therapy
    Medler, Juliane
    Kucka, Kirstin
    Wajant, Harald
    CANCERS, 2022, 14 (11)