Lung Nodule and Functional Changes in Smokers After Smoking Cessation Short-Term Treatment

被引：20

作者：

Maci, Eliana ^{[1
]}

Comito, Francesca ^{[1
]}

Frezza, Anna Maria ^{[1
]}

Tonini, Giuseppe ^{[1
]}

Pezzuto, Aldo ^{[2
]}

机构：

[1] Univ Campus Bio Medico, Dept Med Oncol, I-00128 Rome, Italy

[2] Univ Roma La Sapienza, Fac Med & Chirurg 2, Dept Med, Div Pulmonol, I-00185 Rome, Italy

来源：

CANCER INVESTIGATION | 2014年 / 32卷 / 08期

关键词：

High resolution tomography; Lung nodule evolution; Tobacco; Smoking cessation; SOLITARY PULMONARY NODULES; HIGH-RESOLUTION CT; RESPIRATORY SYMPTOMS; CANCER; BENIGN; TRIAL; PROBABILITY; BUDESONIDE; MANAGEMENT; MORTALITY;

D O I：

10.3109/07357907.2014.919308

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Tobacco smoke causes lung disfunction and inflammation. Methods: Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy. Results: A significant reduction in size of the lung nodules was reported (p = .037) as a trend in number reduction (p = .11). A significant increase in blood arterial oxygen pressure (p < .0001), heart rate reduction (p < .01), and FEV1 increase (p < .0001) was recorded. Conclusions: Smoking cessation reduces number and size of lung nodules and improves in lung functionality.

引用

页码：388 / 393

页数：6

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