Lung Nodule and Functional Changes in Smokers After Smoking Cessation Short-Term Treatment

被引：20
|
作者：
Maci, Eliana [1 ]
Comito, Francesca [1 ]
Frezza, Anna Maria [1 ]
Tonini, Giuseppe [1 ]
Pezzuto, Aldo [2 ]
机构：
[1] Univ Campus Bio Medico, Dept Med Oncol, I-00128 Rome, Italy
[2] Univ Roma La Sapienza, Fac Med & Chirurg 2, Dept Med, Div Pulmonol, I-00185 Rome, Italy
来源：
CANCER INVESTIGATION | 2014年 / 32卷 / 08期
关键词：
High resolution tomography; Lung nodule evolution; Tobacco; Smoking cessation; SOLITARY PULMONARY NODULES; HIGH-RESOLUTION CT; RESPIRATORY SYMPTOMS; CANCER; BENIGN; TRIAL; PROBABILITY; BUDESONIDE; MANAGEMENT; MORTALITY;
D O I：
10.3109/07357907.2014.919308
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: Tobacco smoke causes lung disfunction and inflammation. Methods: Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy. Results: A significant reduction in size of the lung nodules was reported (p = .037) as a trend in number reduction (p = .11). A significant increase in blood arterial oxygen pressure (p < .0001), heart rate reduction (p < .01), and FEV1 increase (p < .0001) was recorded. Conclusions: Smoking cessation reduces number and size of lung nodules and improves in lung functionality.
引用
收藏
页码：388 / 393
页数：6
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