Effect of Electron-Beam Irradiation on Electrospinning Produced Scaffolds

被引：0
|
作者：
Stepanova, A. O. [1 ,2 ]
Korobeinikov, M. V. [3 ]
Yunoshev, A. S. [4 ]
Laktionov, P. P. [1 ,2 ]
机构：
[1] Academician EN Meshalkin, Novosibirsk Res Inst Circulat Pathol, Novosibirsk, Russia
[2] Inst Chem Biol & Fundamental Med SB RAS, Novosibirsk, Russia
[3] Inst Nucl Phys, Novosibirsk, Russia
[4] Inst Hydrodynam, Novosibirsk, Russia
来源：
2015 INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING AND COMPUTATIONAL TECHNOLOGIES (SIBIRCON) | 2015年
关键词：
electron beam irradiation; electrospinning; PCL; PLGA; Nylon; 6;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The influence of electron beam irradiation on the stiffness, stability and biocompatibility of electrospun scaffolds, produced from Nylon 6, polycaprolactone (PCL) and poly(DL-lactic-co-glicolic acid) (PLGA) was investigated. It was shown that irradiation of the matrices with an electron beam generated by the electron beam accelerator ILA-6 (2.2 MeV, 400 mA:, 10 Hz, "Radiochemical technologies Ltd") can potentially be used for sterilization of the matrices (irradiation by a dose of 25 kGy does not interfere with the mechanical properties of all studied matrices). Irradiation of the matrices produced from PCL by a dose of 100 kGy increases the proportional limit of the material and allowed us to introduce durable regions into the vascular grafts by irradiating the graft through the template with open areas. Electron beam irradiation of the matrices does not interfere with the capacity of the matrices to support adhesion and viability of primary human endotheliocytes at the surfaces of these matrices, as it was shown using Alamar Blue assay.
引用
收藏
页码：39 / 42
页数：4
相关论文
共 50 条
  • [21] Analysis of metal tracks produced by electron-beam irradiation of metal-organic films
    Davidson, MR
    Fan, Y
    Cairns, JA
    Berry, GJ
    Thomson, J
    ELECTRON MICROSCOPY AND ANALYSIS 2001, 2001, (168): : 219 - 222
  • [22] Effect of electron-beam irradiation on characteristics of paper. Part 3: grafts of electron-beam reactive monomer to pulp fibers
    Muto, Naoichi
    Yamazaki, Hildehiko
    Kami Pa Gikyoshi/Japan Tappi Journal, 1999, 53 (11): : 104 - 112
  • [23] Effect of electron-beam irradiation on poly(2-hydroxyethyl methacrylate)
    Pinaeva, Uliana
    EUROPEAN POLYMER JOURNAL, 2023, 189
  • [24] Experiments on electron-beam irradiation effects on junction field effect transistors
    Codreanu, C
    Iliescu, E
    CAS'98 PROCEEDINGS - 1998 INTERNATIONAL SEMICONDUCTOR CONFERENCE, 21ST EDITION, VOLS 1 AND 2, 1998, : 275 - 278
  • [25] The effect of electron-beam irradiation on microbiological properties and sensory characteristics of sausages
    Bouzarjomehri, F.
    Dad, V.
    Hajimohammadi, B.
    Shirrnardi, S. P.
    Salimi, A. Yousefi-Ghaleh
    RADIATION PHYSICS AND CHEMISTRY, 2020, 168
  • [26] Effect of Electron-Beam Irradiation on Ethylene-Methyl Acrylate Copolymer
    Mongal, Nilambar
    Chakraborty, Debabrata
    Bhattacharyya, Rupa
    Chaki, Tapan Kumar
    Bhattacharya, Pinaki
    JOURNAL OF APPLIED POLYMER SCIENCE, 2009, 112 (01) : 28 - 35
  • [27] Effect of electron-beam irradiation on the thermal vulcanization of a natural rubber compound
    Esposito, Leandro H.
    Marzocca, Angel J.
    JOURNAL OF APPLIED POLYMER SCIENCE, 2019, 136 (13)
  • [28] EFFECT OF ELECTRON-BEAM IRRADIATION ON CONDUCTING LANGMUIR-BLODGETT-FILMS
    BARRAUD, A
    RICHARD, J
    VANDEVYVER, M
    SYNTHETIC METALS, 1990, 38 (01) : 127 - 131
  • [29] EFFECT OF ELECTRON-BEAM IRRADIATION PRETREATMENT ON THE ENZYMATIC-HYDROLYSIS OF SOFTWOOD
    KHAN, AW
    LABRIE, JP
    MCKEOWN, J
    BIOTECHNOLOGY AND BIOENGINEERING, 1986, 28 (09) : 1449 - 1453
  • [30] PL spectrum analysis of the effect of electron-beam irradiation on AlGaInP LED
    Yu, Liyuan
    Liu, Chao
    Niu, Pingjuan
    Wu, Yinglei
    Diangong Jishu Xuebao/Transactions of China Electrotechnical Society, 2015, 30 : 123 - 127
12345