Does Regional Lymph Node Irradiation Improve the Outcome of N0 and pN0 Breast Cancer?

被引：3
|
作者：
Gilliot, Olivier [1 ]
Durando, Xavier [2 ]
Abrial, Catherine [3 ]
Belliere, Aurelie [1 ]
Gimbergues, Pierre [4 ]
Thivat, Emilie [3 ]
Planchat, Eloise [3 ]
Lapeyre, Michel [1 ]
Kwiatkowski, Fabrice [5 ]
Toledano, Ivan [1 ]
Chollet, Philippe [2 ]
Nabholtz, Jean-Marc [2 ]
Verrelle, Pierre [1 ]
机构：
[1] Ctr Jean Perrin, Dept Radiat Oncol, F-63011 Clermont Ferrand, France
[2] Ctr Jean Perrin, Dept Med Oncol, F-63011 Clermont Ferrand, France
[3] Ctr Jean Perrin, Dept Clin Res, F-63011 Clermont Ferrand, France
[4] Ctr Jean Perrin, Dept Surg, F-63011 Clermont Ferrand, France
[5] Ctr Jean Perrin, Dept Stat, F-63011 Clermont Ferrand, France
来源：
CANCER INVESTIGATION | 2010年 / 28卷 / 02期
关键词：
Neoadjuvant chemotherapy; Radiation therapy; Breast cancer; Node negative; POSTMASTECTOMY RADIATION IMPROVES; NEOADJUVANT CHEMOTHERAPY; POSTOPERATIVE RADIOTHERAPY; ADJUVANT RADIOTHERAPY; PREMENOPAUSAL WOMEN; MASTECTOMY; SURVIVAL; THERAPY; RISK; RECURRENCE;
D O I：
10.3109/07357900903179658
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This study compares the outcome of 76 patients with N0 breast carcinoma, node-negative at axillary lymph node dissection (pN0) after neoadjuvant chemotherapy (NeoCT), treated with (RLNI+, 39 patients) or without (RLNI-, 37 patients) elective regional lymph node areas irradiation. For RLNI- and RLNI+ groups respectively at 10 years, survival without local-regional recurrence was 95% and 91% (p = .59), survival without distant metastasis was 97% and 78% (p = .018) and overall survival was 96% and 75% (p = .013). Clinical size <4 cm was a strong pronostic factor.
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页码：195 / 200
页数：6
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