Unusual Presentation and Surgical Treatment of a Phosphaturic Mesenchymal Tumor in a Knee

被引:2
|
作者
Sun, Juan [1 ]
Zhou, Xi [2 ]
Xia, Weibo [3 ]
Wu, Huanwen [4 ]
Liu, Shuzhong [2 ]
Wang, Huizhen [5 ]
Liu, Yong [2 ]
机构
[1] Chinese Acad Med Sci& Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Gen Surg, Beijing, Peoples R China
[2] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Orthoped Surg, Beijing, Peoples R China
[3] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Endocrinol, Beijing, Peoples R China
[4] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Pathol, Beijing, Peoples R China
[5] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Peking Union Med Coll, Dept Operating Room, Beijing, Peoples R China
来源
FRONTIERS IN SURGERY | 2022年 / 9卷
关键词
tumour-induced osteomalacia; knee joint; surgery; phosphaturic mesenchymal tumors; polymethylmethacrylate (PMMA);
D O I
10.3389/fsurg.2022.746623
中图分类号
R61 [外科手术学];
学科分类号
摘要
A 30-year-old woman presented to our hospital with an 11-year history of gradually enlarging masses around the left knee and 2-year history of progressively worsening bone pain. Tumor-induced osteomalacia (TIO), a rare paraneoplastic syndrome caused by phosphaturic mesenchymal tumors (PMTs) was suspected, but the postoperative pathology of her two operations was both reported as tenosynovial giant cell tumor (TGCT), making its diagnosis confusing. The possibility of hypophosphatemia, insufficient blood supply, innervation of the left lower limbs, as well as the unclear pathology, make it unreasonable to perform tumor-type knee prosthesis replacement directly. Finally, we placed static polymethylmethacrylate (PMMA) spacer at first, then when the concentration of blood phosphorus level rose to the normal range, the pathology was confirmed to be TIO, the blood supply and innervation was satisfying, tumor-type knee prosthesis replacement was performed. She was discharged post operative day 15 after the prothesis implantation without incident. One and a half years after her surgery, the concentration of blood phosphorus was still in the normal range, the symptom of systemic bone pain had improved significantly, the prosthesis was still in a good position and no recurrence was caught.
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页数:6
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