BAY 1816032, a novel BUB1 kinase inhibitor with potent antitumor activity

被引:2
|
作者
Siemeister, Gerhard
Mengel, Anne
Bone, Wilhelm
Schroder, Jens
Zitzmann-Kolbe, Sabine
Briem, Hans
Fernandez-Montalvan, Amaury E.
Holton, Simon
Monning, Ursula
von Ahsen, Oliver
Johanssen, Sandra
Cleve, Arwed
Hitchcock, Marion
Meyer, Kirstin
von Nussbaum, Franz
Brands, Michael
Mumberg, Dominik
Ziegelbauer, Karl
机构
关键词
D O I
10.1158/1538-7445.AM2017-287
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
287
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Inhibition of the serine/threonine kinase BUB1 reverses taxane resistance in prostate cancer
    Martinez, Maria J.
    Lyles, Rolando D. Z.
    Peinetti, Nahuel
    Grunfeld, Alex M.
    Burnstein, Kerry L.
    [J]. ISCIENCE, 2023, 26 (09)
  • [32] Dual function of the Bub1 kinase in the spindle checkpoint and the DNA damage response.
    Wang, H.
    Yang, C.
    Xu, Y.
    Brinkman, K. L.
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2011, 22
  • [33] BUB1 Immunolocalization in Breast Carcinoma: Its Nuclear Localization as a Potent Prognostic Factor of the Patients
    Takagi, Kiyoshi
    Miki, Yasuhiro
    Shibahara, Yukiko
    Nakamura, Yasuhiro
    Ebata, Akiko
    Watanabe, Mika
    Ishida, Takanori
    Sasano, Hironobu
    Suzuki, Takashi
    [J]. HORMONES & CANCER, 2013, 4 (02): : 92 - 102
  • [34] BUB1 Immunolocalization in Breast Carcinoma: Its Nuclear Localization as a Potent Prognostic Factor of the Patients
    Kiyoshi Takagi
    Yasuhiro Miki
    Yukiko Shibahara
    Yasuhiro Nakamura
    Akiko Ebata
    Mika Watanabe
    Takanori Ishida
    Hironobu Sasano
    Takashi Suzuki
    [J]. Hormones and Cancer, 2013, 4 : 92 - 102
  • [35] In vivo antitumor activity of NVP-AEW541 -: A novel, potent, and selective inhibitor of the IGF-IR kinase
    García-Echeverría, C
    Pearson, MA
    Marti, A
    Meyer, T
    Mestan, J
    Zimmermann, J
    Gao, JP
    Brueggen, J
    Capraro, HG
    Cozens, R
    Evans, DB
    Fabbro, D
    Furet, P
    Porta, DG
    Liebetanz, J
    Martiny-Baron, G
    Ruetz, S
    Hofmann, F
    [J]. CANCER CELL, 2004, 5 (03) : 231 - 239
  • [36] Development of a novel lactate dehydrogenase A inhibitor with potent antitumor activity and immune activation
    Du, Mengyan
    Yu, Ting
    Zhan, Qinjinge
    Li, Han
    Zou, Yiping
    Geng, Meiyu
    Meng, Tao
    Xie, Zuoquan
    [J]. CANCER SCIENCE, 2022, 113 (09) : 2974 - 2985
  • [37] Bub1 Kinase and Sgo1 Modulate Pericentric Chromatin in Response to Altered Microtubule Dynamics
    Haase, Julian
    Stephens, Andrew
    Verdaasdonk, Jolien
    Yeh, Elaine
    Bloom, Kerry
    [J]. CURRENT BIOLOGY, 2012, 22 (06) : 471 - 481
  • [38] The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma
    Ciciro, Ylenia
    Ragusa, Denise
    Nevado, Paloma Tejera
    Lattanzio, Rossano
    Sala, Gianluca
    Desrochers, Tessa
    Millard, Melissa
    Andersson, Mattias K.
    Stenman, Goeran
    Sala, Arturo
    [J]. FEBS LETTERS, 2024, 598 (02) : 252 - 265
  • [39] Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
    Ricke, Robin M.
    Jeganathan, Karthik B.
    van Deursen, Jan M.
    [J]. JOURNAL OF CELL BIOLOGY, 2011, 193 (06): : 1049 - 1064
  • [40] Expression of Bub1 gene correlates with tumor proliferating activity in human gastric carcinomas
    Shigeishi, H
    Oue, N
    Kuniyasu, H
    Wakikawa, A
    Yokozaki, H
    Ishikawa, T
    Yasui, W
    [J]. PATHOBIOLOGY, 2001, 69 (01) : 24 - 29