Adjunctive fast repetitive transcranial magnetic stimulation in depression

被引:42
|
作者
Anderson, Ian M.
Delvai, Nicola A.
Ashim, Bettadapura
Ashim, Sindhu
Lewin, Cherry
Singh, Vineet
Sturman, Daniel
Strickland, Paul L.
机构
[1] Univ Manchester, Neurosci & Psychiat Unit, Manchester M13 9PT, Lancs, England
[2] Merseycare NHS Trust, Manchester, Lancs, England
[3] Spinney Partnerships Care Atherton, Manchester, Lancs, England
基金
英国惠康基金;
关键词
D O I
10.1192/bjp.bp.106.028019
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The place of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression remains unclear. In this sham-controlled study we determined the efficacy and acceptability of fast, left frontal rTMS given three times a week over 4-6 weeks to 29 patients with depression (79% treatment-resistant). The procedure was generally well tolerated and more effective than sham treatment (55 v 7% responding, P < 0.05), with improvement maintained to 12 weeks. This therapy could be a useful addition to available treatments but further research is needed to determine the optimum treatment parameters.
引用
收藏
页码:533 / 534
页数:2
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