Developmental signalling: A careful balancing act

被引:19
|
作者
Lemaire, P [1 ]
Yasuo, H [1 ]
机构
[1] Univ Mediterranee AP de Marseille, CNRS, INSERM, Inst Biol Dev Marseille, F-13288 Marseille, France
关键词
D O I
10.1016/S0960-9822(98)70146-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Embryos of arthropods and chordates are patterned along the dorso-ventral axis by a gradient of secreted morphogens of the Bmp4/Dpp family. This gradient now appears to be shaped by the opposing activities of Bmp-sequestering proteins, on the one hand, and Bmp-releasing metalloproteases, on the other.
引用
收藏
页码:R228 / +
页数:5
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