The gas-phase basicities of matrix-assisted laser desorption/ionization matrices

被引:44
|
作者
Steenvoorden, RJJM [1 ]
Breuker, K [1 ]
Zenobi, R [1 ]
机构
[1] ETH Zurich, Dept Chem, CH-8092 Zurich, Switzerland
来源
EUROPEAN MASS SPECTROMETRY | 1997年 / 3卷 / 05期
关键词
MALDI; FT-ICR; proton affinity; fragmentation; matrix;
D O I
10.1255/ejms.165
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
The gas-phase basicities of three common matrices used in matrix-assisted laser desorption/ionization (MALDI) have been investigated using laser desorption with Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. In bracketing type experiments, laser-desorbed ions from 2,5-dihydroxy-benzoic acid, alpha-cyano-4-hydroxy-cinnamic acid and sinapic acid were tested for their ability to protonate test substances, This study was not limited to protonated matrix species but also included prominent fragments.
引用
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页码:339 / 346
页数:8
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