Current Status of Probiotics as Supplements in the Prevention and Treatment of Infectious Diseases

被引:20
|
作者
Li, Xinquan [1 ]
Wang, Qiang [1 ]
Hu, Xiafen [1 ]
Liu, Wanxin [1 ]
机构
[1] Wuhan Univ Sci & Technol, Med Coll, Hubei Prov Key Lab Occupat Hazard Identificat & C, Inst Infect Immunol & Tumor Microenvironm, Wuhan, Peoples R China
关键词
probiotics; infectious disease; microbiota; antibiotics; microecology; STREPTOCOCCUS-SALIVARIUS K12; LACTOBACILLUS-RHAMNOSUS GG; INTERNATIONAL SCIENTIFIC ASSOCIATION; INTERFERING ALPHA-STREPTOCOCCI; RESPIRATORY-TRACT INFECTIONS; SECRETORY OTITIS-MEDIA; CLOSTRIDIUM-DIFFICILE; BACTERIAL VAGINOSIS; ANTIBIOTIC-RESISTANCE; LACTATIONAL MASTITIS;
D O I
10.3389/fcimb.2022.789063
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Probiotics play an important role against infectious pathogens via their effects on the epithelium, the production of antimicrobial compounds, and competitive exclusion. Administration of probiotic supplements may reduce the risk of infectious diseases and the use of antibiotics, hence contributing to a reduction or a delay of the development of multi-resistant bacteria. Infection is a constant concern for people who experience recurrent infections, and antibiotic treatment usually fails due to antibiotic resistance. Therefore, an infection can lead to severe illness and hospitalization if left untreated. A growing number of studies have demonstrated promising results for a variety of probiotic strains used to prevent or treat acute and recurrent infectious diseases, but additional standardized clinical research is needed.
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页数:12
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