Designer probiotics for the prevention and treatment of human diseases

被引：71
|
作者：
Chua, Koon Jiew [1 ,2 ]
Kwok, Wee Chiew [1 ,2 ]
Aggarwal, Nikhil [1 ,2 ]
Sun, Tao [1 ,2 ]
Chang, Matthew Wook [1 ,2 ]
机构：
[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem, Singapore, Singapore
[2] Natl Univ Singapore, NUS Synthet Biol Clin & Technol Innovat SynCTI, Singapore, Singapore
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2017年 / 40卷
基金：
英国医学研究理事会;
关键词：
SALMONELLA-TYPHIMURIUM; BACTERIA DETECT; PSEUDOMONAS-AERUGINOSA; MUCOSAL IMMUNITY; DELIVERY; EXPRESSION; ANTIGEN; COLITIS; PROTEIN; TUMORS;
D O I：
10.1016/j.cbpa.2017.04.011
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Various studies have shown the beneficial effects of probiotics in humans. The use of synthetic biology to engineer programmable probiotics that specifically targets cancer, infectious agents, or other metabolic diseases has gained much interest since the last decade. Developments made in synthetic probiotics as therapeutics within the last three years will be discussed in this review.
引用
收藏
页码：8 / 16
页数：9
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