ZrO2-supported Cu(II)-β-cyclodextrin complex: construction of 2,4,5-trisubstituted-1,2,3-triazoles via azide-chalcone oxidative cycloaddition and post-triazole alkylation

被引：36

作者：

Girish, Yarabally R. ^{[1
]}

Kumar, Kothanahally S. Sharath ^{[1
]}

Muddegowda, Umashankar ^{[2
]}

Lokanath, Neartur Krishnappagowda ^{[3
]}

Rangappa, Kanchugarakoppal S. ^{[1
]}

Shashikanth, Sheena ^{[1
]}

机构：

[1] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India

[2] KSOU, Dept Studies Chem, Mysore 570006, Karnataka, India

[3] Univ Mysore, Dept Studies Phys, Mysore 570006, Karnataka, India

来源：

RSC ADVANCES | 2014年 / 4卷 / 99期

关键词：

ONE-POT SYNTHESIS; CLICK-CHEMISTRY; REGIOSELECTIVE SYNTHESIS; TERMINAL ALKYNES; SODIUM-AZIDE; EFFICIENT SYNTHESIS; HIV-1; PROTEASE; BORONIC ACIDS; 1,2,3-TRIAZOLES; NANOPARTICLES;

D O I：

10.1039/c4ra09970b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient one-pot three-component stepwise approach for the synthesis of N-2-substituted-1,2,3-triazoles from chalcones, sodium azide and esters has been developed using a recoverable and reusable ZrO2 nanoparticle-supported Cu(II)-beta-cyclodextrin complex as a catalyst. N-2 alkylation of triazoles using different aryl-alkyl esters without any additives has been achieved for the first time. The one-pot operation, atom-economical nature, regioselectivity and good yields are the noteworthy features of this protocol. The reusability of the prepared nanocatalyst was successfully examined four times without any appreciable loss in catalytic activity.

引用

页码：55800 / 55806

页数：7

共 13 条

[11] Supported NHC-Benzimi@Cu Complex as a Magnetically Separable and Reusable Catalyst for the Multicomponent and Click Synthesis of 1,4-Disubstituted 1,2,3-Triazoles via Huisgen 1,3-Dipolar Cycloaddition
Arvind Pawar
Shivanand Gajare
Ashutosh Jagdale
Sandip Patil
Wilson Chandane
Gajanan Rashinkar
Suresh Patil
Catalysis Letters, 2022, 152 : 1854 - 1868
[12] One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles via Huisgen 1,3-dipolar cycloaddition catalysed by SiO2-Cu(I) oxide and single crystal X-ray analysis of 1-benzyl-4-phenyl-1H-1,2,3-triazole
Gupta, Manjulla
Gupta, Monika
Paul, Satya
Kant, Rajni
Gupta, Vivek K.
MONATSHEFTE FUR CHEMIE, 2015, 146 (01): : 143 - 148
[13] One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles via Huisgen 1,3-dipolar cycloaddition catalysed by SiO2–Cu(I) oxide and single crystal X-ray analysis of 1-benzyl-4-phenyl-1H-1,2,3-triazole
Manjulla Gupta
Monika Gupta
Satya Paul
Rajni Kant
Vivek K. Gupta
Monatshefte für Chemie - Chemical Monthly, 2015, 146 : 143 - 148

← 1 2 →