Beneficial Effects of Kombucha Tea on Alloxan-Induced Hyperglycemia in Rats

被引:0
|
作者
Bakr, El-Sayed H. [1 ,2 ]
Shaikhomar, Osama A. [3 ]
Header, Eslam A. [1 ,2 ]
Doraib, Mousa A. Abo [4 ]
Shaikhomar, Bassam O. [5 ]
机构
[1] UQU, Clin Nutr Dept, Fac Appl Med Sci, Mecca, Saudi Arabia
[2] Menoufia Univ, Fac Home Econ, Nutr & Food Sci Dept, Shibin Al Kawm, Al Minufiyah, Egypt
[3] Umm Al Qura Univ, Fac Med, Physiol Dept, Mecca, Saudi Arabia
[4] Administrator Nutr Adm Makkah Reg Hlth Affairs, Mecca, Saudi Arabia
[5] Umm Al Qura Univ, Chem Dept, Appl Sci, Mecca, Saudi Arabia
来源
BIOSCIENCE RESEARCH | 2021年 / 18卷 / 01期
关键词
Kombucha tea; hyperglycemia; rats; red and green tea; DENSITY-LIPOPROTEIN; OXIDATIVE STRESS; CHOLESTEROL;
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Recently people have started consuming kombucha tea as a healthful substitute to conventional fizzy drinks. The beneficial effects of kombucha tea on alloxan-induced hyperglycemia in rats is the aim of this research. In this study, kombucha tea was prepared using green and red tea, kambucha "mushroom and sugare. A total of 30 adult male Wistar Albino rats divided into 6 groups (5 rats each) were used in the current study. One group was fed basal diet only for 45 successive days and used as non-diabetic negative control group, while the other groups were used for induction of diabitic model after intraperitoneal injection of alloxan at a dose level of 150 mg/kg b.wt. One of the diabetic rat groups received only basal diet for the same period and used as positive control group, however other 4 diebtic groups were fed on 250 and 500 mg/kg b. wt., of kumbucha red and green tea, respectively. The obtained results revealed that all hyperglycemic rats then orally administered with kombucha red and green tea at two doses (250 and 500mg/kg b.wt.) showed significant increases in BWG, FER and HDL, whereas significant decreases in serum glucose, T.C, T.G, LDL, VLDL, AST, ALT, ALP, creatinine, urea and uric acid as compared to control positive group. The investigation concluded that kombucha red and green tea had hypoglycemic properties and could be used as folk remedies for hyperglycemia.
引用
收藏
页码:429 / 438
页数:10
相关论文
共 50 条
  • [41] Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats
    El-Demerdash, FM
    Yousef, MI
    Abou El-Naga, NI
    FOOD AND CHEMICAL TOXICOLOGY, 2005, 43 (01) : 57 - 63
  • [42] Effects of Hirudotherapy in Alloxan-induced Diabetic Male Rats: Histopathological and Biochemical Changes
    Namjou, Abdolrasoul
    Razavie, Ebrahim
    Heidarian, Esfandiar
    Yazdani, Nasser
    Rafieian-Kopaei, Mahmoud
    JUNDISHAPUR JOURNAL OF NATURAL PHARMACEUTICAL PRODUCTS, 2023, 18 (03)
  • [43] Effects of Opium Addiction on Some Serum Factors of Alloxan-Induced Diabetic Rats
    Khaled, M. I.
    Hatem, A. M.
    Shaaban, M. A.
    Gawish, E. H. E.
    TOXICOLOGIC PATHOLOGY, 2009, 37 (01) : 138 - 138
  • [44] Antihyperglycemic and antihyperlipidemic effects of olive and fenugreek leaves in alloxan-induced diabetic rats
    Elsadek, M. F.
    Abd El-Basset, Mona A.
    Almajwal, A.
    PROGRESS IN NUTRITION, 2013, 15 (03): : 175 - 183
  • [45] Antihyperglycemic and antihyperlipidemic effects of fermented Rhynchosia nulubilis in alloxan-induced diabetic rats
    Kim M.J.
    Ha B.J.
    Toxicological Research, 2013, 29 (1) : 15 - 19
  • [46] Anti-diabetic effects of walnut oil on alloxan-induced diabetic rats
    Rahimi, Parivash
    Kabiri, Najmeh
    Asgary, Sedigheh
    Setorki, Mahbubeh
    AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY, 2011, 5 (24): : 2655 - 2661
  • [47] Effects of 18α-glycyrrhizin on the pharmacodynamics and pharmacokinetics of glibenclamide in alloxan-induced diabetic rats
    Ao, Ying
    Chen, Jie
    Yue, Jiang
    Peng, Ren-Xiu
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 587 (1-3) : 330 - 335
  • [48] Hypoglycemic, antilipidemic and antioxidant effects of valproic acid in alloxan-induced diabetic rats
    Akindele, Abidemi J.
    Otuguor, Edafe
    Singh, Dhirendra
    Ota, Duncan
    Benebo, Adokiye S.
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 762 : 174 - 183
  • [49] THE BONE STRUCTURE IN ALLOXAN-INDUCED DIABETES MELLITUS IN RATS
    HERNBERG, CA
    ACTA MEDICA SCANDINAVICA, 1952, 142 (04): : 274 - 283
  • [50] Hypoglycaemic effect of galactooligosaccharides in alloxan-induced diabetic rats
    Sangwan, Vikas
    Tomar, Sudhir K.
    Ali, Babar
    Singh, Ram R. B.
    Singh, Ashish K.
    JOURNAL OF DAIRY RESEARCH, 2015, 82 (01) : 70 - 77