Brace treatment is the most commonly used non-surgical treatment method for adolescent idiopathic scoliosis (AIS). This study determined whether curve progression can be predicted by how often and how well children with AIS wear their braces. Twenty subjects (3M, 17F) who were diagnosed with AIS and had worn their braces from six months up to I year participated into this study. All subjects were prescribed Boston style braces and have now completed their brace treatment. On average, the brace was used 57% of the prescribed time. Peterson's risk of progression (Risser sign, age, apex of curve and imbalance of curve) predicted only 3-8% of the curve progression of brace subjects. Knowing how brace subjects used their braces in terms of brace tightness increases the prediction rate to 12-21%; and wear time further increase it to 25-36%. Adding the multiple of brace tightness and wear time improves curve progression prediction to 41-54%. To be most effective, the brace should be worn as prescribed in both tightness and time manners.