Role of nuclear factor κB in the central nervous system

被引：0
|
作者：
Malek, Robert
Borowicz, Kinga K.
Jargiello, Malgorzata
Czuczwar, Stanislaw J.
机构：
[1] Med Univ Lublin, Dept Pathophysiol, PL-20090 Lublin, Poland
[2] Inst Agr Med, Dept Phytopathol, PL-20950 Lublin, Poland
来源：
PHARMACOLOGICAL REPORTS | 2007年 / 59卷 / 01期
关键词：
MF-kappa B; neuroprotection; neurodegeneration; FOCAL CEREBRAL-ISCHEMIA; DNA-BINDING ACTIVITY; TRANSCRIPTION FACTOR; INDUCED NEUROPROTECTION; LEUKOCYTE INFILTRATION; HIPPOCAMPAL-NEURONS; REDUCES INFARCTION; SODIUM-SALICYLATE; OXIDATIVE STRESS; P50; SUBUNIT;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The aim of this review was to assemble current literature data on nuclear factor kappa B (NF-kappa B). Many authors believe that NF-kappa B, a transcription factor, has essential influence on the regulation of numerous genes in the organism. In this review, we have focused Oil the role of NF-kappa B and its target genes in the central nervous system functioning. Unfortunately, the contribution of NF-kappa B to neuroprotection or to neurodegeneration is not clear, yet. Therefore, its exact role in these processes and potential applications in pharmacology are still to be determined.
引用
收藏
页码：25 / 33
页数：9
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