Skin Barrier and Inflammation Genes Associated with Atopic Dermatitis are Regulated by Interleukin-13 and Modulated by Tralokinumab In vitro

被引：16
|
作者：
Tollenaere, Maxim A. X. [1 ]
Litman, Thomas [1 ]
Moebus, Lena [2 ]
Rodriguez, Elke [2 ]
Stoelzl, Dora [2 ]
Drerup, Katharina [2 ]
Werfel, Thomas [3 ]
Schmitt, Jochen [4 ]
Norsgaard, Hanne [1 ]
Weidinger, Stephan [2 ]
机构：
[1] LEO Pharma AS, Skin Res, Ballerup, Denmark
[2] Univ Hosp Schleswig Holstein, Dept Dermatol Venereol & Allergol, Campus Kiel, Kiel, Germany
[3] Hannover Med Sch, Dept Dermatol Allergol & Venereol, Div Immunodermatol & Allergy Res, Hannover, Germany
[4] Tech Univ Dresden, Med Fac Carl Gustav Carus, Ctr Evidence Based Hlth Care ZEGV, Dresden, Germany
来源：
ACTA DERMATO-VENEREOLOGICA | 2021年 / 101卷
关键词：
D O I：
10.2340/00015555-3810
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Interleukin-13 Inhibitors in the Treatment of Atopic Dermatitis: The Role of Tralokinumab
    Dattola, Annunziata
    Tolone, Martina
    Amore, Emanuele
    Bennardo, Luigi
    Trovato, Federica
    Amato, Simone
    Grieco, Teresa
    Richetta, Antonio Giovanni
    Pellacani, Giovanni
    Skroza, Nevena
    Nistico, Steven Paul
    DERMATOLOGY PRACTICAL & CONCEPTUAL, 2024, 14 (03):
  • [2] Impact of interleukin-13 on epidermal inflammation in atopic dermatitis
    Wittmann, M
    Purwar, R
    Werfel, T
    EXPERIMENTAL DERMATOLOGY, 2006, 15 (03) : 192 - 192
  • [3] Targeting interleukin-13 with tralokinumab reduces S. aureus abundance in adolescents with atopic dermatitis
    Beck, Lisa A.
    Weidinger, Stephan
    Tauber, Marie
    Saeki, Hidehisa
    Irvine, Alan D.
    Eichenfield, Lawrence
    Werfel, Thomas
    Arlert, Petra
    Kurbasic, Azra
    Ropke, Mads A.
    Paller, Amy
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2023, 89 (03) : AB92 - AB92
  • [4] The hidden sentinel of the skin: An overview on the role of interleukin-13 in atopic dermatitis
    Napolitano, Maddalena
    di Vico, Francesca
    Ruggiero, Angelo
    Fabbrocini, Gabriella
    Patruno, Cataldo
    FRONTIERS IN MEDICINE, 2023, 10
  • [5] Interleukin-13: Targeting an underestimated cytokine in atopic dermatitis
    Bieber, Thomas
    ALLERGY, 2020, 75 (01) : 54 - 62
  • [6] Biological agents targeting interleukin-13 for atopic dermatitis
    Chiricozzi, Andrea
    Gori, Niccolo
    Maurelli, Martina
    Gisondi, Paolo
    Caldarola, Giacomo
    De Simone, Clara
    Peris, Ketty
    Girolomoni, Giampiero
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2022, 22 (05) : 651 - 659
  • [7] PERIOSTIN AND INTERLEUKIN-13: INDEPENDENT ASSOCIATIONS WITH ATOPIC DERMATITIS
    Mohta, Alpana
    ACTA DERMATO-VENEREOLOGICA, 2023, 103 : 38 - 38
  • [8] The pleiotropic role of interleukin-13 in the pathogenesis of atopic dermatitis
    Dekkers, Coco
    de Bruin-Weller, Marjolein
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 191 (03) : 316 - 317
  • [9] Interleukin-13 as a promising therapeutic target for alopecia areata associated with atopic dermatitis
    Oiso, Naoki
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 2024, 63 (03) : E84 - 269
  • [10] Blockade of interleukin-13 signalling improves skin barrier function and biology in patients with moderate-to-severe atopic dermatitis
    Sander, Nicole
    Stoelzl, Dora
    Fonfara, Melina
    Hartmann, Jan
    Harder, Inken
    Suhrkamp, Ina
    Jakasa, Ivone
    van den Bogaard, Ellen
    van Vlijmen-Willems, Ivonne
    Szymczak, Silke
    Rodriguez, Elke
    Gerdes, Sascha
    Weidinger, Stephan
    BRITISH JOURNAL OF DERMATOLOGY, 2024, 191 (03) : 344 - 350
12345