Accelerating HIV-1 Vaccine Efficacy Trials

被引：15
|
作者：
Barouch, Dan H. [1 ,2 ,3 ]
Michael, Nelson L. [4 ]
机构：
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Ctr Virol & Vaccine Res, Boston, MA 02215 USA
[2] MIT, Ragon Inst MGH, Cambridge, MA 02139 USA
[3] Harvard, Cambridge, MA 02139 USA
[4] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD 20910 USA
来源：
CELL | 2014年 / 159卷 / 05期
关键词：
DOUBLE-BLIND; GAG/POL/NEF VACCINE; HVTN; 503/PHAMBILI; RHESUS-MONKEYS; SOUTH-AFRICA; PHASE; 2H; INFECTION; CHALLENGES;
D O I：
10.1016/j.cell.2014.10.046
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：969 / 972
页数：4
相关论文
共 50 条
  • [21] HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing
    Lyons, Danielle E.
    Kumar, Priti
    Roan, Nadia R.
    Defechereux, Patricia A.
    Feschotte, Cedric
    Lange, Ulrike C.
    Murthy, Niren
    Sameshima, Pauline
    Verdin, Eric
    Ake, Julie A.
    Parsons, Matthew S.
    Nath, Avindra
    Gianella, Sara
    Smith, Davey M.
    Kallas, Esper G.
    Villa, Thomas J.
    Strange, Richard
    Mwesigwa, Betty
    Furler O'Brien, Robert L.
    Nixon, Douglas F.
    Ndhlovu, Lishomwa C.
    Valente, Susana T.
    Ott, Melanie
    [J]. VIRUSES-BASEL, 2023, 15 (11):
  • [22] Conserved multiepitope vaccine constructs: A potent HIV-1 therapeutic vaccine in clinical trials
    Akbari, Elahe
    Seyedinkhorasani, Masoud
    Bolhassani, Azam
    [J]. BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, 2023, 27 (03):
  • [23] Immunogenicity and Efficacy of a Therapeutic HIV-1 Vaccine (HIVAX™) in HIV Patients on HAART
    Tung, F.
    Tung, J. K.
    Castro, J.
    Boliva, H.
    Fischl, M. A.
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2013, 29 (11) : A173 - A173
  • [24] HIV-1 subtype C vaccine: Waiting in wings for the human trials
    Seth, Pradeep
    [J]. International Journal of Biotechnology, 2007, 9 (3-4) : 360 - 380
  • [25] Some statistical issues in the design of HIV-1 vaccine and treatment trials
    Gilbert, PB
    [J]. STATISTICAL METHODS IN MEDICAL RESEARCH, 2000, 9 (03) : 207 - 229
  • [26] HIV-1 Infections During Vaccine Trials: Identifying New Epitopes For Differential Diagnosis Of HIV-1 Infections In The Face Of Vaccine -Induced Antibodies
    Hana Golding
    James Needham
    Surender Khurana
    [J]. Retrovirology, 2
  • [27] Cellular immunity to human immunodeficiency virus type 1 (HIV-1) clades: Relevance to HIV-1 vaccine trials in Uganda
    Cao, HY
    Mani, I
    Vincent, R
    Mugerwa, R
    Mugyenyi, P
    Kanki, P
    Ellner, J
    Walker, BD
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2000, 182 (05): : 1350 - 1356
  • [28] Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8+ T cells with limited breadth of HIV-1 inhibition
    Hayes, Peter J.
    Cox, Josephine H.
    Coleman, Adam R.
    Fernandez, Natalia
    Bergin, Philip J.
    Kopycinski, Jakub T.
    Nitayaphan, Sorachai
    Pitisuttihum, Punnee
    de Souza, Mark
    Duerr, Ann
    Morgan, Cecilia
    Gilmour, Jill W.
    [J]. AIDS, 2016, 30 (11) : 1703 - 1712
  • [29] HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection:: compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates
    Heeney, J
    Åkerblom, L
    Barnett, S
    Bogers, W
    Davis, D
    Fuller, D
    Koopman, G
    Lehner, T
    Mooij, P
    Morein, B
    Morghen, CD
    Rosenwirth, B
    Verschoor, E
    Wagner, R
    Wolf, H
    [J]. IMMUNOLOGY LETTERS, 1999, 66 (1-3) : 189 - 195
  • [30] HIV-1 Infections During Vaccine Trials: Identifying New Peptides for Differential Diagnosis of HIV-1 Infections in the Face of Vaccine-generated Antibodies
    Surender Khurana
    James Needham
    Hana Golding
    [J]. Retrovirology, 2
12345