Accelerating HIV-1 Vaccine Efficacy Trials

被引:15
|
作者
Barouch, Dan H. [1 ,2 ,3 ]
Michael, Nelson L. [4 ]
机构
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Ctr Virol & Vaccine Res, Boston, MA 02215 USA
[2] MIT, Ragon Inst MGH, Cambridge, MA 02139 USA
[3] Harvard, Cambridge, MA 02139 USA
[4] Walter Reed Army Inst Res, US Mil HIV Res Program, Silver Spring, MD 20910 USA
关键词
DOUBLE-BLIND; GAG/POL/NEF VACCINE; HVTN; 503/PHAMBILI; RHESUS-MONKEYS; SOUTH-AFRICA; PHASE; 2H; INFECTION; CHALLENGES;
D O I
10.1016/j.cell.2014.10.046
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:969 / 972
页数:4
相关论文
共 50 条
  • [1] Lessons from HIV-1 vaccine efficacy trials
    Excler, Jean-Louis
    Michael, Nelson L.
    [J]. CURRENT OPINION IN HIV AND AIDS, 2016, 11 (06) : 607 - 613
  • [2] Sieve analysis in HIV-1 vaccine efficacy trials
    Edlefsen, Paul T.
    Gilbert, Peter B.
    Rolland, Morgane
    [J]. CURRENT OPINION IN HIV AND AIDS, 2013, 8 (05) : 432 - 436
  • [3] Trends in HIV-1 incidence in a cohort of prostitutes in Kenya: Implications for HIV-1 vaccine efficacy trials
    Baeten, JM
    Richardson, BA
    Martin, HL
    Nyange, PM
    Lavreys, L
    Ngugi, EN
    Mandaliya, K
    Ndinya-Achola, JO
    Bwayo, JJ
    Kreiss, JK
    [J]. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2000, 24 (05) : 458 - 464
  • [4] Should South Africa be preparing for HIV-1 vaccine efficacy trials?
    Morris, L
    vanderRyst, E
    Gray, C
    [J]. SOUTH AFRICAN MEDICAL JOURNAL, 1997, 87 (03): : 285 - 290
  • [5] Insights from HIV-1 vaccine and passive immunization efficacy trials
    Ahmed, Shamim
    Herschhorn, Alon
    [J]. TRENDS IN MOLECULAR MEDICINE, 2024, 30 (10) : 908 - 912
  • [6] Complex immune correlates of protection in HIV-1 vaccine efficacy trials
    Tomaras, Georgia D.
    Plotkin, Stanley A.
    [J]. IMMUNOLOGICAL REVIEWS, 2017, 275 (01) : 245 - 261
  • [7] Preexisting Adenovirus Seropositivity Is Not Associated With Increased HIV-1 Acquisition in Three HIV-1 Vaccine Efficacy Trials
    Stephenson, Kathryn E.
    Hural, John
    Buchbinder, Susan P.
    Sinangil, Faruk
    Barouch, Dan H.
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2012, 205 (12): : 1806 - 1810
  • [8] Lessons from failure - Preparing for future HIV-1 vaccine efficacy trials
    Graham, BS
    Mascola, JR
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (05): : 647 - 649
  • [9] Preexisting Immunity to Multiple Adenovirus Serotypes is Not Associated with Increased HIV-1 Acquisition in Three HIV-1 Vaccine Efficacy Trials
    Stephenson, K. E.
    Hural, J.
    Buchbinder, S. P.
    Sinangil, F.
    Barouch, D. H.
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2011, 27 (10) : A132 - A133
  • [10] HIV-1 superinfections: omens for vaccine efficacy?
    Fultz, PN
    [J]. AIDS, 2004, 18 (01) : 115 - 119