L-amino acids are allosteric modulators of the calcium-sensing receptor (CaR).

被引：0
|
作者：
Conigrave, AD
Diaz, R
Quinn, SJ
Brown, EM
机构：
[1] Univ Sydney, Dept Biochem, Sydney, NSW 2006, Australia
[2] Childrens Hosp, Div Endocrine, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Div Endocrine Hypertens, Boston, MA 02115 USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2000年 / 15卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
F100
引用
收藏
页码：S209 / S209
页数：1
相关论文
共 50 条
  • [31] The discovery of novel calcium sensing receptor negative allosteric modulators
    Balan, Gayatri
    Bauman, Jonathan
    Bhattacharya, Samit
    Castrodad, Mayda
    Healy, David R.
    Herr, Michael
    Humphries, Paul
    Jennings, Sandra
    Kalgutkar, Amit S.
    Kapinos, Brendon
    Khot, Vishal
    Lazarra, Kimberly
    Li, Mei
    Li, Yan
    Neagu, Constantin
    Oliver, Robert
    Piotrowski, David W.
    Price, David
    Qi, Hong
    Simmons, Holly A.
    Southers, James
    Wei, Liuqing
    Zhang, Yan
    Paralkar, Vishwas M.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (12) : 3328 - 3332
  • [32] Nanobodies as negative allosteric modulators for human calcium sensing receptor
    Cui, Qianqian
    Wang, Lu
    Wang, Haonan
    Chen, Xiaochen
    Han, Li
    Geng, Tengjie
    Kou, Yongjun
    Zhang, Wenqing
    Dai, Mei
    Qiao, Huarui
    Sun, Zengchao
    Li, Lingyun
    Lan, Zhongyun
    Xu, Hongxi
    Xu, Jiaqiang
    Dai, Yuanyuan
    Geng, Yong
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 695
  • [33] Distribution of calcium-sensing receptor (CaR) in duodenopancreatico endocrine tumors
    Komoto, I
    Kato, M
    Imamura, M
    Itami, A
    Hosotani, R
    Doi, R
    Shimada, Y
    [J]. GASTROENTEROLOGY, 1999, 116 (04) : A1139 - A1139
  • [34] Activation of the Calcium-Sensing Receptor by a Subfraction of Amino Acids Contained in Thyroid Drainage Fluid
    Nanoff, Christian
    Yang, Qiong
    Hellinger, Roland
    Hermann, Michael
    [J]. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2024,
  • [35] Characterization of Highly Efficacious Allosteric Agonists of the Human Calcium-Sensing Receptor
    Ma, Jian-Nong
    Owens, Michelle
    Gustafsson, Magnus
    Jensen, Jacob
    Tabatabaei, Ali
    Schmelzer, Kara
    Olsson, Roger
    Burstein, Ethan S.
    [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2011, 337 (01): : 275 - 284
  • [36] Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor
    Katie Leach
    Karen J Gregory
    Irina Kufareva
    Elham Khajehali
    Anna E Cook
    Ruben Abagyan
    Arthur D Conigrave
    Patrick M Sexton
    Arthur Christopoulos
    [J]. Cell Research, 2016, 26 : 574 - 592
  • [37] Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor
    Leach, Katie
    Gregory, Karen J.
    Kufareva, Irina
    Khajehali, Elham
    Cook, Anna E.
    Abagyan, Ruben
    Conigrave, Arthur D.
    Sexton, Patrick M.
    Christopoulos, Arthur
    [J]. CELL RESEARCH, 2016, 26 (05) : 574 - 592
  • [38] Therapeutic Opportunities of Targeting Allosteric Binding Sites on the Calcium-Sensing Receptor
    Diao, Jiayin
    DeBono, Aaron
    Josephs, Tracy M.
    Bourke, Jane E.
    Capuano, Ben
    Gregory, Karen J.
    Leach, Katie
    [J]. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021, 4 (02) : 666 - 679
  • [39] Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose
    Medina, Johan
    Nakagawa, Yuko
    Nagasawa, Masahiro
    Fernandez, Anny
    Sakaguchi, Kazushige
    Kitaguchi, Tetsuya
    Kojima, Itaru
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (44) : 23126 - 23135
  • [40] Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation
    Lee, Heather J.
    Mun, Hee-Chang
    Lewis, Narelle C.
    Crouch, Michael F.
    Culverston, Emma L.
    Mason, Rebecca S.
    Conigrave, Arthur D.
    [J]. BIOCHEMICAL JOURNAL, 2007, 404 : 141 - 149
12345