Synthesis of tetracyclic 5-azaindole analogues by palladium-catalyzed sequential annulation

被引：0
|
作者：
Sung, ND
Yang, OK
Kang, SS
Yum, EK [1 ]
机构：
[1] Chungnam Natl Univ, Dept Chem, Taejon 305764, South Korea
[2] Chungnam Natl Univ, Div Appl Biol & Chem, Taejon 305764, South Korea
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2004年 / 25卷 / 09期
关键词：
tetracyclic 5-azaindole analogues; palladium; catalyst; annulation; 1-aryl alkynes;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Tetracyclic 5-azaindole analogues were prepared by palladium-catalyzed sequential annulation of benzylidene(3-iodopyridinyl-4-yl)amine and 1-aryl substituted internal alkynes under Pd(OAC)(2), n-Bu4NCl, and Et3N at 120 degreesC. The synthetic procedure showed possible diversification of tetracyclic 5-azaindole analogues by varying the 1-aryl substituent in internal alkynes.
引用
收藏
页码：1351 / 1354
页数：4
相关论文
共 50 条
  • [21] Synthesis of the fused tetracyclic spiroindoles via palladium-catalyzed cascade reaction
    Iwata, Akira
    Oishi, Shinya
    Fujii, Nobutaka
    Ohno, Hiroaki
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [22] Enantioselective Synthesis of Ten-Membered Lactones via Palladium-Catalyzed [5+5] Annulation
    Shi, Liu
    Xiong, Qiang
    Wu, Shu-Yi
    Li, Yang
    Shen, Peng
    Lu, Ji
    Ran, Guang-Yao
    ORGANIC LETTERS, 2023, 25 (12) : 2030 - 2035
  • [23] Palladium-Catalyzed Indole and Azaindole Synthesis by Direct Annulation of Electron-Poor o-Chloroanilines and o-Chloroaminopyridines with Aldehydes
    Xu, Zhengren
    Hu, Weimin
    Zhang, Fengying
    Li, Qingjiang
    Lue, Zhiyao
    Zhang, Lihe
    Jia, Yanxing
    SYNTHESIS-STUTTGART, 2008, 24 (24): : 3981 - 3987
  • [24] Solid-phase synthesis of heterocycles via palladium-catalyzed annulation
    Wang, Y
    Huang, TN
    TETRAHEDRON LETTERS, 1998, 39 (52) : 9605 - 9608
  • [25] Palladium-Catalyzed Annulation of Arynes by o-Halobenzamides: Synthesis of Phenanthridinones
    Lu, Chun
    Dubrovskiy, Anton V.
    Larock, Richard C.
    JOURNAL OF ORGANIC CHEMISTRY, 2012, 77 (19): : 8648 - 8656
  • [26] Synthesis of Quinolinones with Palladium-Catalyzed Oxidative Annulation between Acrylamides and Arynes
    Wang, Weiguo
    Peng, Xianglong
    Qin, Xiaoyu
    Zhao, Xiangyun
    Ma, Chen
    Tung, Chen-Ho
    Xu, Zhenghu
    JOURNAL OF ORGANIC CHEMISTRY, 2015, 80 (05): : 2835 - 2841
  • [27] Synthesis of annulated γ-carbolines and heteropolycycles by the palladium-catalyzed intramolecular annulation of alkynes
    Zhang, HM
    Larock, RC
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (13): : 5132 - 5138
  • [28] Synthesis of isocoumarins and α-pyrones via palladium-catalyzed annulation of internal alkynes
    Larock, RC
    Doty, MJ
    Han, XJ
    JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (24): : 8770 - 8779
  • [29] Synthesis of substituted naphthalenes and carbazoles by the palladium-catalyzed annulation of internal alkynes
    Huang, Q
    Larock, RC
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (19): : 7342 - 7349
  • [30] SYNTHESIS OF AROMATIC HETEROCYCLES VIA PALLADIUM-CATALYZED ANNULATION OF INTERNAL ALKYNES
    LAROCK, RC
    YUM, EK
    DOTY, MJ
    SHAM, KKC
    JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (11): : 3270 - 3271
12345