Ascorbic acid: a naturally green and efficient catalyst for one-pot synthesis of N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates under ambient temperature

被引：2

作者：

Mohamadpour, Farzaneh ^{[1
]}

机构：

[1] Islamic Azad Univ, Shiraz Branch, Young Researchers & Elite Club, Shiraz, Iran

来源：

BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY | 2019年 / 9卷 / 06期

关键词：

Ascorbic acid; Green catalyst; N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates; Multi-component reaction; One-pot procedure; 4-COMPONENT DOMINO REACTION; MULTICOMPONENT SYNTHESIS; BIODEGRADABLE CATALYST; CONVENIENT SYNTHESIS; ECO-SAFE; DIHYDRO-2-OXOPYRROLES; INHIBITORS; DERIVATIVES; PIPERIDINES; CAFFEINE;

D O I：

10.33263/BRIAC96.458462

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A naturally green and economical ascorbic acid synthesis of N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates has been accomplished via one-pot four-condensation of dialkylacetylenedicarboxylate, formaldehyde and amines (aromatic and aliphatic) under ambient temperature. The notable advantages of the procedure are green, natural and low-cost catalyst, operational simplicity, eco-friendly, environmentally benign nature, no necessity of chromatographic purification steps, short reaction times and good to high yields.

引用

页码：4458 / 4462

页数：5

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