Using physiologically based pharmacokinetic modelling for in silico-in vitro-in vivo extrapolation to predict chemical exposure

被引：0
|
作者：
Lawless, M. [1 ]
Zhou, H. [1 ]
Fraczkiewicz, G. [1 ]
机构：
[1] Simulat Plus, Lancaster, CA USA
来源：
TOXICOLOGY LETTERS | 2016年 / 258卷
关键词：
D O I：
10.1016/j.toxlet.2016.06.1484
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
P05-016
引用
收藏
页码：S119 / S120
页数：2
相关论文
共 50 条
  • [41] Integration of mechanism-based in vitro methods and quantitative in vitro-in vivo extrapolation (QIVIVE) modelling for prediction of nephrotoxicity
    Mally, A.
    Birk, B.
    DiFiore, S.
    Ellinger, B.
    Jarzina, S.
    Taverne, F.
    Kramer, N.
    TOXICOLOGY LETTERS, 2018, 295 : S27 - S27
  • [42] PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL OF TOPOTECAN TO VERIFY EFFLUX TRANSPORTER IN VITRO IN VIVO EXTRAPOLATION.
    Ning, M.
    Fang, Z.
    Hoeckels-Messemer, J.
    Riedmaier, A. Emami
    Bow, D. A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019, 105 : S64 - S65
  • [43] Integration of In Vitro and In Vivo Models to Predict Cellular and Tissue Dosimetry of Nanomaterials Using Physiologically Based Pharmacokinetic Modeling
    Lin, Zhoumeng
    Aryal, Santosh
    Cheng, Yi-Hsien
    Gesquiere, Andre J.
    ACS NANO, 2022, 16 (12) : 19722 - 19754
  • [44] Novel In Vitro-In Vivo Extrapolation (IVIVE) Method to Predict Hepatic Organ Clearance in Rat
    Ken-ichi Umehara
    Gian Camenisch
    Pharmaceutical Research, 2012, 29 : 603 - 617
  • [45] Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro-in vivo extrapolation
    Algharably, Engi Abdelhady
    Di Consiglio, Emma
    Testai, Emanuela
    Pistollato, Francesca
    Bal-Price, Anna
    Najjar, Abdulkarim
    Kreutz, Reinhold
    Gundert-Remy, Ursula
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [46] Novel In Vitro-In Vivo Extrapolation (IVIVE) Method to Predict Hepatic Organ Clearance in Rat
    Umehara, Ken-ichi
    Camenisch, Gian
    PHARMACEUTICAL RESEARCH, 2012, 29 (02) : 603 - 617
  • [47] Application of adverse outcome pathways and quantitative in vitro-in vivo extrapolation (QIVIVE) modelling for risk assessment based on in vitro data
    Mally, A.
    Birk, B.
    Di Fiore, S.
    Ellinger, B.
    Jarzina, S.
    Reiser, P.
    Taverne, F.
    Kramer, N.
    TOXICOLOGY LETTERS, 2019, 314 : S140 - S140
  • [48] Computational Predictions of Mycophenolic Acid Exposure after Oral Administration using a Joined In Vitro-In Vivo Extrapolation and Physiologically-Based Pharmacokinetic Modeling Approach in Caucasian and Chinese Healthy Volunteers and Patients With Varying Degree of Renal Impairment
    Joshi, Rujuta
    Venkataramanan, Raman
    Kalluri, Hari Varun
    TRANSPLANTATION, 2017, 101 (05) : S13 - S14
  • [49] Quantitative Prediction of Glucuronidation in Humans Using the In Vitro-In Vivo Extrapolation Approach
    Wu, Baojian
    Dong, Dong
    Hu, Ming
    Zhang, Shuxing
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2013, 13 (11) : 1343 - 1352
  • [50] An integrated QSPR-PBPK modelling approach for in vitro-in vivo extrapolation of pharmacokinetics in rats
    Kamgang, E.
    Peyret, T.
    Krishnan, K.
    SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2008, 19 (7-8) : 669 - 680
12345