A Cervical Histopathology Dataset for Computer Aided Diagnosis of Precancerous Lesions

被引:14
|
作者
Meng, Zhu [1 ]
Zhao, Zhicheng [1 ,2 ]
Li, Bingyang [1 ]
Su, Fei [1 ,2 ]
Guo, Limei [3 ]
机构
[1] Beijing Univ Posts & Telecommun, Sch Artificial Intelligence, Beijing 100876, Peoples R China
[2] Beijing Key Lab Network Syst & Network Culture, Beijing 100876, Peoples R China
[3] Peking Univ, Dept Pathol, Sch Basic Med Sci, Hosp 3,Hlth Sci Ctr, Beijing 100044, Peoples R China
基金
中国国家自然科学基金;
关键词
Histopathology; Lesions; Cancer; Annotations; Supervised learning; Feature extraction; Image segmentation; Cervical histopathology; classification; dataset; segmentation; weakly supervised learning; BREAST-CANCER;
D O I
10.1109/TMI.2021.3059699
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Cervical cancer, as one of the most frequently diagnosed cancers worldwide, is curable when detected early. Histopathology images play an important role in precision medicine of the cervical lesions. However, few computer aided algorithms have been explored on cervical histopathology images due to the lack of public datasets. In this article, we release a new cervical histopathology image dataset for automated precancerous diagnosis. Specifically, 100 slides from 71 patients are annotated by three independent pathologists. To show the difficulty of the task, benchmarks are obtained through both fully and weakly supervised learning. Extensive experiments based on typical classification and semantic segmentation networks are carried out to provide strong baselines. In particular, a strategy of assembling classification, segmentation, and pseudo-labeling is proposed to further improve the performance. The Dice coefficient reaches 0.7833, indicating the feasibility of computer aided diagnosis and the effectiveness of our weakly supervised ensemble algorithm. The dataset and evaluation codes are publicly available. To the best of our knowledge, it is the first public cervical histopathology dataset for automated precancerous segmentation. We believe that this work will attract researchers to explore novel algorithms on cervical automated diagnosis, thereby assisting doctors and patients clinically.
引用
收藏
页码:1531 / 1541
页数:11
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