fMRI reveals amygdala activation to human faces in social phobics

被引：265
|
作者：
Birbaumer, N
Grodd, W
Diedrich, O
Klose, U
Erb, M
Lotze, M
Schneider, F
Weiss, U
Flor, H
机构：
[1] Humboldt Univ, Dept Psychol, D-10117 Berlin, Germany
[2] Univ Tubingen, Inst Med Psychol & Behav Neurobiol, D-72074 Tubingen, Germany
[3] Univ Tubingen, CNS, Sect Expt Magnet Resonance, D-72076 Tubingen, Germany
[4] Univ Dusseldorf, Dept Psychiat, D-40629 Dusseldorf, Germany
来源：
NEUROREPORT | 1998年 / 9卷 / 06期
关键词：
amygdala; fear conditioning; functional magnetic resonance imaging; social phobia;
D O I：
10.1097/00001756-199804200-00048
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
FUNCTIONAL magnetic resonance imaging was used to determine the activation of the amygdala while seven social phobics and five healthy controls were exposed to slides of neutral faces as well as aversive odor stimuli. The amygdala was selectively activated in the social phobics during presentation of the face stimuli. The data show for the first time that the amygdala is active in human phobics when they are exposed to potentially fear-relevant stimuli. Further research is needed to determine the extent to which overactivation of the amygdala precedes or is a consequence of phobia. (C) 1998 Rapid Science Ltd.
引用
收藏
页码：1223 / 1226
页数：4
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