Bariatric Surgery: A Potential Treatment for Type 2 Diabetes in Youth

被引：21

作者：

Shah, Amy S. ^{[1
,2
]}

D'Alessio, David ^{[3
,4
]}

Ford-Adams, Martha E. ^{[5
,6
]}

Desai, Ashish P. ^{[6
,7
]}

Inge, Thomas H. ^{[2
,8
]}

机构：

[1] Cincinnati Childrens Hosp, Dept Pediat, Cincinnati, OH USA

[2] Univ Cincinnati, Cincinnati, OH USA

[3] Duke Univ, Sch Med, Dept Med, Div Metab Endocrinol & Nutr, Durham, NC 27706 USA

[4] Durham VA Med Ctr, Durham, NC USA

[5] Kings Coll Hosp London, Dept Child Hlth, London, England

[6] Kings Coll London, GKT Sch Med Educ, London WC2R 2LS, England

[7] Kings Coll Hosp London, Dept Pediat Surg, London, England

[8] Cincinnati Childrens Hosp, Dept Surg, Cincinnati, OH USA

来源：

DIABETES CARE | 2016年 / 39卷 / 06期

基金：

美国国家卫生研究院;

关键词：

LONG-TERM REMISSION; BETA-CELL FUNCTION; OBESE CHILDREN; WEIGHT-LOSS; GLUCOSE-TOLERANCE; GLYCEMIC CONTROL; ADOLESCENTS; MELLITUS; INTERVENTION; IMPROVEMENTS;

D O I：

10.2337/dc16-0067

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Type 2 diabetes, once referred to as adult-onset diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is growing evidence regarding the epidemiology of type 2 diabetes in youth and its multisystem health consequences, treatment options have lagged and progression of disease occurs even with aggressive medical therapy. Increasing interest in the application of bariatric surgery for adolescents with type 2 diabetes has evolved in part because of the evidence demonstrating improvement or remission in many adults with diabetes after surgery. Here, we review the burden of type 2 diabetes in youth including its associated complications, discuss the outcomes and complications of bariatric surgery in adolescents with diabetes, and conclude with recommendations for future research and options for refinement of the use of bariatric surgery in this patient population.

引用

页码：934 / 940

页数：7

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