Exploitation of novel wild type solventogenic strains for butanol production

被引：12
|
作者：
Xin, Fengxue [1 ,2 ]
Yan, Wei [1 ]
Zhou, Jie [1 ,2 ]
Wu, Hao [1 ,2 ]
Dong, Weiliang [1 ,2 ]
Ma, Jiangfeng [1 ,2 ]
Zhang, Wenming [1 ,2 ]
Jiang, Min [1 ,2 ]
机构：
[1] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, State Key Lab Mat Oriented Chem Engn, Puzhu South Rd 30, Nanjing 211816, Jiangsu, Peoples R China
[2] Nanjing Tech Univ, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Nanjing 211816, Jiangsu, Peoples R China
来源：
BIOTECHNOLOGY FOR BIOFUELS | 2018年 / 11卷
基金：
中国国家自然科学基金;
关键词：
Solventogenic Clostridium sp; Fermentation pattern; Substrate utilization; Novel genus; LIPASE-CATALYZED ESTERIFICATION; ACETOBUTYLICUM ATCC 824; CLOSTRIDIUM-ACETOBUTYLICUM; CATABOLITE REPRESSION; ESCHERICHIA-COLI; CRUDE GLYCEROL; BUTYL-BUTYRATE; D-XYLOSE; FERMENTATION; BEIJERINCKII;
D O I：
10.1186/s13068-018-1252-3
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Butanol has been regarded as an important bulk chemical and advanced biofuel; however, large scaling butanol production by solventogenic Clostridium sp. is still not economically feasible due to the high cost of substrates, low butanol titer and yield caused by the toxicity of butanol and formation of by-products. Renewed interests in biobutanol as biofuel and rapid development in genetic tools have spurred technological advances to strain modifications. Comprehensive reviews regarding these aspects have been reported elsewhere in detail. Meanwhile, more wild type butanol producers with unique properties were also isolated and characterized. However, few reviews addressed these discoveries of novel wild type solventogenic Clostridium sp. strains. Accordingly, this review aims to comprehensively summarize the most recent advances on wild type butanol producers in terms of fermentation patterns, substrate utilization et al. Future perspectives using these native ones as chassis for genetic modification were also discussed.
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页数：8
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