Improving Objective Measurements of the Tumour-Stroma Ratio in Breast Cancer Using Polarized Light Microscopy

被引:0
|
作者
Sprenger, Jillian [1 ]
Murray, Ciara [2 ]
Lad, Jigar [1 ]
Jones, Blake [1 ]
Thomas, Georgia [1 ]
Nofech-Mozes, Sharon [3 ]
Khorasani, Mohammadali [4 ]
Vitkin, Alex [1 ,5 ]
机构
[1] Univ Toronto, Dept Med Biophys, Toronto, ON, Canada
[2] Univ Hlth Network, Lab Med Program, Toronto, ON, Canada
[3] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[4] Univ British Columbia, Dept Surg, Victoria, BC, Canada
[5] Univ Toronto, Dept Radiat Oncol, Toronto, ON, Canada
来源
关键词
INDEPENDENT PREDICTOR; SURVIVAL; CELLS;
D O I
10.1117/12.2615729
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Polarized light microscopy can be used to objectively quantify tumour-stroma ratio (TSR), a prognostic indicator validated in several cancers. Polarimetric results correctly differentiated between high- and low-stroma samples, and future work holds promise for improved separation.
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页数:3
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