Pre-clinical proof-of-concept for CAR-T Cells directed against the tumour antigen 5T4 in the treatment of haematological malignancies

被引：0
|
作者：
Blount, D. G. [1 ]
Soyombo, M. [1 ]
Moyce, L. [1 ]
Kelleher, M. [1 ]
Harrop, R. [1 ]
机构：
[1] Oxford BioMed, Oxford, England
来源：
HUMAN GENE THERAPY | 2019年 / 30卷 / 11期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
P106
引用
收藏
页码：A49 / A49
页数：1
相关论文
共 44 条
  • [41] 2B4 costimulatory domain enhancing cytotoxic ability of anti-CD5 chimeric antigen receptor engineered natural killer cells against T cell malignancies
    Yingxi Xu
    Qian Liu
    Mengjun Zhong
    Zhenzhen Wang
    Zhaoqi Chen
    Yu Zhang
    Haiyan Xing
    Zheng Tian
    Kejing Tang
    Xiaolong Liao
    Qing Rao
    Min Wang
    Jianxiang Wang
    [J]. Journal of Hematology & Oncology, 12
  • [42] Preliminary results of a first in human Phase 1 clinical trial to demonstrate safety and feasibility of chimeric antigen receptor T (CART) cells directed against c-Met in the treatment of breast cancer
    Tchou, J.
    Zhang, P. J.
    Levine, B. L.
    Zhao, Y.
    Matro, J.
    DeMichele, A.
    Amy, C.
    Schuchter, L.
    Plesa, G.
    Vonderheide, R. H.
    June, C.
    [J]. CANCER RESEARCH, 2017, 77
  • [43] IL-10+T follicular helper cells (CXCR5+PD-1+CD4+TFH10) promote immune tolerance and regulate b cell function following allergen immunotherapy: A proof-of-concept cross-sectional study
    Sharif, H.
    Fear, D.
    Laisuan, W.
    Zhang, J.
    Yi, Y.
    Parkin, R.
    Fedina, O.
    Nadal, Vila G.
    Scadding, G.
    Durham, S. R.
    Shamji, M. H.
    [J]. ALLERGY, 2020, 75 : 46 - 46
  • [44] Interim Safety Analysis: a Phase I Trial of High Dose Therapy and Autologous Stem Cell Transplantation Followed By Infusion of Chimeric Antigen Receptor Modified T-Cells (19-28z CAR-T) Directed Against CD19+B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma (B-NHL)
    Sauter, Craig S.
    Riviere, Isabelle
    Bernal, Yvette J.
    Wang, Xiuyan
    Purdon, Terence J.
    Yoo, Sarah
    Moskowitz, Craig H.
    Giralt, Sergio
    Matasar, Matthew J.
    Curran, Kevin J.
    Park, Jae H.
    Sadelain, Michel
    Brentjens, Renier J.
    [J]. BLOOD, 2014, 124 (21)
12345