This is a case of herpes simplex encephalitis (HSE) examined with Tc-99m-ethyl cysteinate dimer (ECD) and Tc-99m-hexamethyl propyleneamine oxime (HMPAO) SPECT. Static images obtained with Tc-99m-ECD showed a reduced tracer uptake of the temporal lobe but focal hyperactivity using Tc-99m-HMPAO. Dynamic images indicated regional increase of cerebral blood perfusion with both tracers. Technetium-99m-ECD had rapid washout from the inflammed tissue, while Tc-99m-HMPAO had avid uptake. Hypofixation of Tc-99m-ECD leads to failure to detect the characteristic finding of temporal robe hyperemia in acute HSE.
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Univ Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, BelgiumUniv Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, Belgium
Waelbers, Tim
Peremans, Kathelijne
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Univ Ghent, Dept Vet Med Imaging & Small Anim Orthopaed, B-9820 Merelbeke, BelgiumUniv Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, Belgium
Peremans, Kathelijne
Vermeire, Simon
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Univ Ghent, Dept Vet Med Imaging & Small Anim Orthopaed, B-9820 Merelbeke, BelgiumUniv Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, Belgium
Vermeire, Simon
Piron, Koen
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Univ Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, BelgiumUniv Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, Belgium
Piron, Koen
Polis, Ingeborgh
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Univ Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, BelgiumUniv Ghent, Dept Med & Clin Biol Small Anim, B-9820 Merelbeke, Belgium