Synthesis of deuterated 4,4′-diaminodiphenylsulfone (Dapsone) and related analogs

被引：4

作者：

Gannett, PM ^{[1
]}

Johnson, EM ^{[1
]}

Grimes, MA ^{[1
]}

Myers, AL ^{[1
]}

Deavers, RE ^{[1
]}

Tracy, TS ^{[1
]}

机构：

[1] W Virginia Univ, Sch Pharm, Dept Basic Pharmaceut Sci, Morgantown, WV 26506 USA

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 2003年 / 46卷 / 02期

关键词：

4,4 '-diaminophenyl sulfone; Dapsone; deuterated; synthesis;

D O I：

10.1002/jlcr.649

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A general scheme for the synthesis of 4,4'-diaminodiphenylsulfone-d(5) (Dapsone) from aniline-d(5) is described. The method may have general application and the preparation of the related analogs, 4,4'-dimethylaminodiphenyl sulfone from aniline-d(5) and 4,4'-dimethoxydiphenyl sulfone from phenol-d(5), is also described. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：107 / 114

页数：8

共 50 条

[41] Synthesis of 4,4'-Dicyanostilbene
Fu, SC
Sah, PPT
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1942, 64 : 1482 - 1482
[42] SYNTHESIS OF 4,4'-OXYBISPYRIDINE
ROCKLEY, JE
SUMMERS, LA
CHEMISTRY & INDUSTRY, 1981, (03) : 97 - 97
[43] SYNTHESIS OF 4,4'-BIIMIDAZOLES
CLIFF, MD
PYNE, SG
SYNTHESIS-STUTTGART, 1994, (07): : 681 - 682
[44] SYNTHESIS OF 4,4'-DIMETHYLSPHONDINE
ZAWADOWSKI, T
MAZUR, J
ACTA POLONIAE PHARMACEUTICA, 1980, 37 (03): : 289 - 291
[45] Synthesis of 4,4′-bisphenolformal
Hao, JT
Boyles, D
Bendler, JT
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 225 : U364 - U364
[46] STUDIES IN THE SULFONE SERIES .2. MONO-N-HETEROCYCLIC DERIVATIVES OF 4,4'-DIAMINODIPHENYLSULFONE
AMSTUTZ, ED
FEHNEL, EA
WOODS, JW
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1947, 69 (08) : 1922 - 1925
[47] Unusual twisted intramolecular charge transfer processes of 4,4′-diaminodiphenylsulfone in β-cyclodextrin:: a study by electronic spectra
Enoch, I. V. Muthu Vijayan
Swaminathan, Meenakshisundaram
JOURNAL OF CHEMICAL RESEARCH, 2006, (08) : 523 - 526
[48] First synthesis of alkylthio-substituted 4,4'-biphenoquinones and 4,4'-biphenohydroquinones (4,4'-biphenyldiols)
Morita, Y
Kashiwagi, A
Nakasuji, K
JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (21): : 7464 - 7468
[49] STEROIDS .85. SYNTHESIS OF 4-METHYL AND 4,4-DIMETHYL HORMONE ANALOGS
RINGOLD, HJ
ROSENKRANZ, G
JOURNAL OF ORGANIC CHEMISTRY, 1957, 22 (06): : 602 - 605
[50] Cure kinetics of an epoxy system containing tetraglycidyl-4,4′-diaminodiphenylmethane (TGDDM) and a multifunctional Novolac glycidyl ether cured with 4,4′-diaminodiphenylsulfone (DDS)
L. Barral
J. Cano
J. López
P. Nogueira
M. J. Abad
C. Ramírez
Journal of thermal analysis, 1997, 50 : 409 - 423

← 1 2 3 4 5 →