Is homocysteine a cardiovascular risk?

被引：0

作者：

Kassab, A ^{[1
]}

Ferchichi, S ^{[1
]}

Amira, D ^{[1
]}

Thabet, M ^{[1
]}

Mahdhaoui, A ^{[1
]}

Charfeddine, B ^{[1
]}

Nagara, M ^{[1
]}

Moukaouem, J ^{[1
]}

Ben Iimam, H ^{[1
]}

Ammar, H ^{[1
]}

Laradi, S ^{[1
]}

Miled, A ^{[1
]}

机构：

[1] CHU Farhat Hached, Toxicol & Biochem Lab, Sousse, Tunisia

来源：

EUROMEDLAB 2003: PROCEEDINGS OF THE 15TH IFCC-FESCC EUROPEAN CONGRESS OF CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2003年

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Several studies showed that hyperhomocysteinemia is associated with an increased risk of atherosclerotic vascular disease. Our aim was To investigate: the use of systematic detection of hyperhomocysteinemia in a coronary population, to cite several treatment recommendations which were indicated by other clinical trials of homocysteine lowering for cardiovascular outcome prevention. We measured plasmatic homocysteine concentration in 100 coronary patients (56.50 +/- 11.80 years old) and 40 healthy subjects (57.45 +/- 8.66 years old). Homocysteine concentration was significantly increased in coronary patients compared to control subjects (19.79 +/- 7.95 imol/l vs 13.08 +/- 2.66 imol/l). Hyperhomocysteine prevalence was 72% among our coronary patients who showed mostly moderate acute myocardial infarction (AMI). Patients with posterior AMI showed significant higher homocysteine concentration than inferior AMI. This study allowed us to estimate homocysteine prevalence and to appreciate the usefulness of a homocysteine systematic measure in coronary patients.

引用

页码：537 / 540

页数：4

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