A Monte Carlo study of bone-tissue interface microdosimeters

被引:1
|
作者
Cho, I-Chun [1 ,2 ,3 ]
Chen, Fang-Hsin [1 ,2 ,3 ]
Chao, Tsi-Chian [1 ,2 ,3 ]
Tung, Chuan-Jong [1 ,2 ,3 ]
机构
[1] Chang Gung Univ, Dept Med Imaging & Radiol Sci, Taoyuan 333, Taiwan
[2] Chang Gung Univ, Inst Radiol Res, Med Phys Res Ctr, Taoyuan 333, Taiwan
[3] Chang Gung Mem Hosp, Taoyuan 333, Taiwan
关键词
Bone; B100; Microdosimetry; TEPC; Lineal energy; RELATIVE BIOLOGICAL EFFECTIVENESS; CLINICAL PROTON-BEAMS; IONIZING-RADIATION; IRRADIATION; EQUIVALENCE; SIMULATIONS; PARTICLES; ELECTRONS; SPECTRA; CELLS;
D O I
10.1016/j.apradiso.2018.07.018
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Radiation-induced bone diseases were frequently reported in radiotherapy patients. To study the diseases, microdosimeters were constructed with walls of A150-A150, A150-B100, B100-A150 and B100-B100 interfaces. Monte Carlo simulations of these microdosimeters were performed to determine the lineal energy spectra of an interface site at different depths in water for 230 MeV protons. Comparing these spectra with data of ICRU tissue and bone walls, better agreements were found at shallow depths for protons and delta-rays than deep depths for nuclear interactions.
引用
收藏
页码:193 / 200
页数:8
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