The one-step synthesis of MIBK via catalytic distillation: A preliminary pilot scale study

This paper reports the results of a preliminary pilot scale study in which MIBK was successfully produced in a single catalytic distillation reactor utilizing two separate catalytic reaction zones. The MIBK productivity was relatively low, primarily due to hydrogenation catalyst deactivation and the relatively low hydrogen partial pressures in this experiment. However, the experimental results are insightful and elucidate the immediate challenges that must be addressed in this ongoing process development. Specifically, improved catalyst performance is required. Catalyst characterization via DRIFT spectroscopy indicates that the ketone group of MIBK is strongly adsorbed on the commercial Pd/alumina hydrogenation catalyst used in this study.