Cucurbitane-Type Triterpenoids from Momordica charantia

被引:0
|
作者
Chen, Chiy-Rong [1 ]
Liao, Yun-Wen [2 ]
Kuo, Yueh-Hsiung [3 ,4 ]
Hsu, Jue-Liang [2 ]
Chang, Chi-I [2 ]
机构
[1] Natl Taitung Univ, Dept Life Sci, Taitung 95002, Taiwan
[2] Natl Pingtung Univ Sci & Technol, Dept Biol Sci & Technol, Pingtung 91201, Taiwan
[3] China Med Univ, Coll Pharm, Dept Chinese Pharmaceut Sci & Chinese Med Resourc, Taichung 404, Taiwan
[4] Asia Univ, Dept Biotechnol, Taichung 413, Taiwan
关键词
Momordica charantia; Cucurbitaceae; Fruit; Triterpenoid; Cucurbitane; HYDROPEROXIDE-INDUCED HEPATOTOXICITY; ISOLATED MAJOR COMPOUNDS; CYTOTOXIC ACTIVITY; FRUIT PULP; GLYCOSIDES; STEMS; CONSTITUENTS; LEAVES; SAPONINS; CELLS;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new cucurbitane-type triterpenoids, 7 beta,23(S)-dimethoxycucurbita-5,24-dien-3 beta-ol (1) and 3 beta-hydroxycucurbita-6,23(425-trien-5 beta,19-olide (2), and two known cucurbitane-type triterpenoids, 7 beta,25-dimethoxycucurbita-5,23(E)-dien-3 beta-ol (3) and karavilagenin D (4), were isolated from the fruit pulp of Momordica charantia. Their structures were established by means of 1D and 2D NMR spectra (H-1, C-13, COSY, HMQC, HMBC, and NOESY) as well as EI-MS data.
引用
收藏
页码:889 / 892
页数:4
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