On a trinity role of the survival and hazard functions of the two-stage carcinogenesis models

被引:1
|
作者
Zheng, Q [1 ]
机构
[1] Natl Ctr Toxicol Res, Div Biometry & Risk Assessment, Jefferson, AR 72079 USA
关键词
carcinogenesis model; model indistinguishability; survival function; hazard function; birth-and-death process;
D O I
10.1080/03610919808813471
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Three types of the two-stage models that were based on the linear birth-and-death processes were originally envisioned by Kendall (1960) as tools for modeling the carcinogenic process. While two of the three models enjoy widespread applicability, the other has lain fallow so far. This note reports that, as far as the survival and hazard functions are concerned, all three models are equivalent. In addition to giving a proof of the claim, the note also discusses some of the implications within the context of applications of the two-stage models.
引用
收藏
页码:137 / 145
页数:9
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