Synthesis of 7-membered cyclic oxamides: Novel HIV-1 protease inhibitors

被引：28
|
作者：
Jadhav, PK
Man, HW
机构：
[1] Du Pont Merck Pharmaceutical Company, Chem. and Phys. Sciences Department, Experimental Station, Wilmington, DE 19880-0500
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 08期
关键词：
D O I：
10.1016/0040-4039(96)00013-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An intermediate with three chiral centers, constructed by two key reactions viz. asymmetric allylboration and Sharpless epoxidation, has been used for the synthesis of novel 7-membered cyclic oxamides.
引用
收藏
页码：1153 / 1156
页数：4
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