Angioimmunoblastic T-cell lymphoma with autoimmune thrombocytopenia: A report of two cases

被引：6

作者：

Oka, Kuniyuki ^{[1
]}

Nagayama, Reizo ^{[1
]}

Yatabe, Yasushi ^{[2
]}

Iijima, Shigeruko ^{[1
]}

Mori, Naoyoshi ^{[3
]}

机构：

[1] Mito Saiseikai Gen Hosp, Mito, Ibaraki 3114198, Japan

[2] Aichi Canc Ctr Hosp, Dept Pathol & Mol Diag, Nagoya, Aichi 464, Japan

[3] Nakatsugawa City Hosp, Gifu, Japan

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2010年 / 206卷 / 04期

关键词：

Angioimmunoblastic T-cell lymphoma (AILT); Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD); Autoimmune thrombocytopenia (AIT); Platelet-associated immunoglobulin G (PAIgG); HYPERPLASTIC GERMINAL-CENTERS; IMMUNOBLASTIC LYMPHADENOPATHY;

D O I：

10.1016/j.prp.2009.04.002

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We report two patients, a 68-year-old man (Case 1) and a 66-year-old man (Case 2), with polyclonal gammopathy, lymphadenopathy, thrombocytopenia, and high platelet-associated IgG (PAIgG) level. We initially diagnosed them as having angioimmunoblastic lymphadenopathy with dysproteinemia (AILD). From confirmation of clear cells by careful observation and detection of rearrangement bands of T cell receptors by Southern blot hybridization analysis, we finally concluded that their diagnoses were compatible with angioimmunoblastic T-cell lymphoma (AILT). AILT with autoimmune thrombocytopenia (AIT) is very rare, and all the reported cases were Japanese ones. (C) 2009 Elsevier GmbH. All rights reserved.

引用

页码：270 / 275

页数：6

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