First report of a medullar cord compression secondary to osseous plasmacytoma successfully treated with bortezomib and dexamethasone

被引：4
|
作者：
Espanol, I. [1 ]
Martinez, A. [1 ]
Lopez, M. D. [1 ]
Iturbe, T. [1 ]
Tejedor, A. [1 ]
Garcia, M. C. [1 ]
Cavero, S. [1 ]
Funes, C. [2 ]
Ibanez, J. [1 ]
机构：
[1] Hosp Univ Santa Ma del Rosell, Serv Hematol, Cartagena 30203, Spain
[2] Hosp Univ Virgen Arrixaca, Serv Hematol, Murcia, Spain
来源：
LEUKEMIA RESEARCH | 2010年 / 34卷 / 04期
关键词：
Spinal cord compression; Osseous plasmacytoma; Bortezomib; RELAPSED MULTIPLE-MYELOMA; EXTRAMEDULLARY PLASMACYTOMA; SOLITARY PLASMACYTOMA; BONE; COMBINATION; EMERGENCY;
D O I：
10.1016/j.leukres.2009.09.029
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Medullar cord compression secondary to osseous plasmacytomas affecting the vertebrae is an oncological emergency. A 75-year-old woman with recurrent osseous plasmacytomas and thoracic spinal cord compression, previously treated with radiotherapy, was successfully treated with bortezomib and dexamethasone. Three years later, when the plasmacytoma and spinal cord compression relapsed, she was retreated with the same therapeutic scheme, achieving a new complete clinical remission. This is the first reported case of an excellent response to the combination of bortezomib and dexamethasone for spinal cord compression due to osseous plasmacytoma. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：E97 / E99
页数：3
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