A selective hybrid fluorescent sensor for fructose detection based on a phenylboronic acid and BODIPY-based hydrophobicity probe

被引：8
|
作者：
Kashiwazaki, Gengo [1 ]
Watanabe, Ryo [1 ]
Nishikawa, Akihiro [1 ]
Kawamura, Koyori
Kitayama, Takashi [1 ]
Hibi, Takao [2 ]
机构：
[1] Kindai Univ, Major Adv Biosci, Grad Sch Agr, 3327-204,Nakamachi, Nara 6318505, Japan
[2] Fukui Prefectural Univ, Fac Biosci & Biotechnol, Dept Biosci & Biotechnol, 4-1-1 Matsuoka Kenjojima, Fukui 9101195, Japan
来源：
RSC ADVANCES | 2022年 / 12卷 / 24期
关键词：
BORONIC ACID; DYES; WATER; CHEMOSENSORS; SENSITIVITY; BINDING; PROTEIN; DESIGN; DONOR;
D O I：
10.1039/d2ra01569b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Fructose is widely used in the food industry. However, it may be involved in diseases by generating harmful advanced glycation end-products. We have designed and synthesized a novel fluorescent probe for fructose detection by combining a phenylboronic acid group with a BODIPY-based hydrophobicity probe. This probe showed a linear fluorescence response to d-fructose concentration in the range of 100-1000 mu M, with a detection limit of 32 mu M, which is advantageous for the simple and sensitive determination of fructose.
引用
收藏
页码：15083 / 15090
页数：8
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