The HOMR-Now! Model Accurately Predicts 1-Year Death Risk for Hospitalized Patients on Admission

被引:18
|
作者
van Walraven, Carl [1 ,2 ,3 ,4 ]
Forster, Alan J. [1 ,2 ,3 ,5 ]
机构
[1] Univ Ottawa, Dept Med, ASB1-003 1053,Carling Ave, Ottawa, ON K1Y 4E9, Canada
[2] Univ Ottawa, Dept Epidemiol & Community Med, Ottawa, ON, Canada
[3] Ottawa Hosp Res Inst, Ottawa, ON, Canada
[4] Inst Clin Evaluat Sci ICES uOttawa, Ottawa, ON, Canada
[5] Ottawa Hosp, Ottawa, ON, Canada
来源
AMERICAN JOURNAL OF MEDICINE | 2017年 / 130卷 / 08期
关键词
Administrative data; Calibration; Discrimination; Hospitalization; Mortality; Multivariate logistic regression; Risk index; Risk model; Risk score; Survival; FRACTIONAL POLYNOMIALS; MORTALITY; VALIDATION;
D O I
10.1016/j.amjmed.2017.03.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: The Hospital-patient One-year Mortality Risk (HOMR) score is an externally validated index using health administrative data to accurately predict the risk of death within 1 year of admission to the hospital. This study derived and internally validated a HOMR modification using data that are available when the patient is admitted to the hospital. METHODS: From all adult hospitalizations at our tertiary-care teaching hospital between 2004 and 2015, we randomly selected one per patient. We added to all HOMR variables that could be determined from our hospital's data systems on admission other factors that might prognosticate. Vital statistics registries determined vital status at 1 year from admission. RESULTS: Of 2,06,396 patients, 32,112 (15.6%) died within 1 year of admission to the hospital. The HOMR-now! model included patient (sex, comorbidities, living and cancer clinic status, and 1-year death risk from population-based life tables) and hospitalization factors (admission year, urgency, service and laboratory-based acuity score). The model explained that more than half of the total variability (Regenkirke's R-2 value of 0.53) was very discriminative (C-statistic 0.92), and accurately predicted death risk (calibration slope 0.98). CONCLUSION: One-year risk of death can be accurately predicted using routinely collected data available when patients are admitted to the hospital. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:991.e9 / 991.e16
页数:8
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